Evidence map›Paper›PMID 41373646›Full record

ArticleInternational journal of molecular sciences2025

Electronic Cigarette Exposure Induces Adverse Cellular Alterations in Skeletal Muscle in Male Mice Subjected to a High-Fat Diet.

Juan Carlos Rivera, Jorge Espinoza-Derout, Kamrul Hasan, Candice J Lao, Julian Wilson, Yin Tintut, Xuesi M Shao, Maria C Jordan, Kenneth P Roos, Yanjun Liu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Juan Carlos RiveraDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Jorge Espinoza-DeroutDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Kamrul HasanDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.ORCID 0000-0002-6561-3524
Candice J LaoDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Julian WilsonDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.ORCID 0000-0002-8883-6843
Yin TintutDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0003-0156-2307
Xuesi M ShaoDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Maria C JordanDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Kenneth P RoosDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-2823-5069
Yanjun LiuDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Amiya P Sinha-HikimDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
Vishwajeet PuriDepartment of Biomedical Sciences and Diabetes Institute, Ohio University Heritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Theodore C FriedmanDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA.

Funding

Workshop for Junior Biostatisticians in Health ResearchU54MD007598 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI David Sane Martins · 2012 to 2026
$60.0M
Targeting PARP Proteins in electronic cigarettes-induced cardiac dysfunctionR16GM153622 · NIGMS · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI Jorge Espinoza-Derout · 2024 to 2026
$434k
Role of CARF in Insulin Resistance and Non Alcoholic Fatty Liver disease NAFLDSC2GM125551 · NIGMS · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI HASAN, KAMRUL M · 2019 to 2021
$431k
Therapeutic Roles for NAD+ Metabolism in Electronic Cigarettes-Induced Cardiac DysfunctionSC2GM135127 · NIGMS · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI ESPINOZA-DEROUT, JORGE · 2020 to 2022
$431k
California TRDRP 28CP-0040DOD CDMRP PR190942NIGMS NIH HHS R16 GM153622NIGMS NIH HHS R16GM153622NIGMS NIH HHS SC2GM125551NIGMS NIH HHS SC2GM135127NIH R25 DA050723NIMHD AXIS U54MD007598NIMHD NIH HHS S21-MD000103NIMHD NIH HHS U54 MD007598
6 · The paper itself

Abstract

Electronic cigarettes (E-Cig) are a new way of delivering nicotine, gaining popularity among adolescents and young adults, who often do not realize their harmful effects. Although the adverse effects of E-Cigs on the liver and heart have been demonstrated, their effects on the skeletal muscle have not been well studied. In this study, we evaluated the skeletal muscle effects of E-Cig aerosol, delivered in a manner similar to human vaping, in a mouse model of obesity induced by a high-fat diet (HFD). C57BL/6 mice, fed either a normal chow diet (NCD) or HFD, were exposed to either saline aerosol control or aerosol generated from Blu PLUS

Indexed as

Diet, High-FatElectronic Nicotine Delivery SystemsMuscle, SkeletalObesityAMP-Activated Protein KinasesAnimalsMaleMiceMice, Inbred C57BLNicotineAMP-Activated Protein KinasesNicotineelectronic cigarettehigh-fat dietnicotineobesityskeletal muscle

Identifiers

PMID41373646
PMCPMC12691771

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.