Evidence map›Paper›PMID 41373583›Full record

ArticleInternational journal of molecular sciences2025

A Pilot Study on the Potential Pathological Link Between Oxidative Stress Markers and Renal Function in People Living with HIV.

Joel Choshi, Haskly Mokoena, Helen C Steel, Brian T Flepisi, Kabelo Mokgalaboni, Wendy N Phoswa, Gerald Maarman, Sihle E Mabhida, Bongani B Nkambule, Phiwayinkosi V Dludla and 1 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joel ChoshiDepartment of Physiology and Environmental Health, University of Limpopo, Sovenga 0727, South Africa.
Haskly MokoenaDepartment of Physiology and Environmental Health, University of Limpopo, Sovenga 0727, South Africa.ORCID 0000-0001-9054-7242
Helen C SteelDepartment of Immunology, University of Pretoria, Pretoria 0001, South Africa.ORCID 0000-0001-5899-4472
Brian T FlepisiDepartment of Pharmacology, University of the Witwatersrand, Braamfontein, Johannesburg 2050, South Africa.ORCID 0000-0002-0628-4636
Kabelo MokgalaboniDepartment of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Florida Campus, Roodepoort 1710, South Africa.ORCID 0000-0002-3224-7433
Wendy N PhoswaDepartment of Life and Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Florida Campus, Roodepoort 1710, South Africa.ORCID 0000-0002-7769-4528
Gerald MaarmanCARMA: Centre for Cardio-Metabolic Research in Africa, Division of Medical Physiology, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town 8000, South Africa.ORCID 0000-0003-3336-5594
Sihle E MabhidaNon-Communicable Diseases Research Unit, South African Medical Research Council, Tygerberg 7505, South Africa.
Bongani B NkambuleSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Phiwayinkosi V DludlaSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.ORCID 0000-0001-5965-3610
Sidney HanserDepartment of Physiology, School of Medicine, Sefako Makgatho Health Science University, Ga-Rankuwa 0208, South Africa.ORCID 0000-0002-6719-8512

Funding

National Research Foundation (NRF) 107249National Research Foundation (NRF) 117829National Research Foundation (NRF) 141929)
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) infection remains a major health burden in Sub-Saharan Africa, despite the widespread use of antiretroviral therapy (ART). Oxidative stress contributes to HIV-related comorbidities, including renal dysfunction. However, the role of oxidative stress in kidney impairment among people living with HIV (PLWH) is not fully understood. This cross-sectional study included PLWH on ART (

Indexed as

BiomarkersHIV InfectionsKidneyOxidative StressAdultAntioxidantsCross-Sectional StudiesCystatin CFemaleGlomerular Filtration RateHumansMaleMalondialdehydeMiddle AgedPilot ProjectsSuperoxide DismutaseAntioxidantsBiomarkersCystatin CMalondialdehydeSuperoxide Dismutaseantiretroviral therapyoxidative stresspeople living with HIVrenal function

Identifiers

PMID41373583
PMCPMC12692261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.