Evidence map›Paper›PMID 41373575›Full record

ReviewInternational journal of molecular sciences2025

Targeting Survivin: Now I Become Death, the Destroyer of Cells.

Mia Fanuzzi, Shuhua Zheng, Craig M Horbinski, Maryam A Shaaban, Harrshavasan Congivaram, Ruochen Du, Shashwat Tripathi, Lisa Hurley, Priya Kumthekar, Atique Ahmed and 3 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mia FanuzziDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Shuhua ZhengMalnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0003-3903-3080
Craig M HorbinskiDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Maryam A ShaabanDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0009-0000-5871-977X
Harrshavasan CongivaramDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Ruochen DuDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-0580-5196
Shashwat TripathiDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Lisa HurleyDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Priya KumthekarMalnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-5923-0677
Atique AhmedDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0003-4795-0188
Daniel J BratMalnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Maciej S LesniakDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-0096-5107
Amy B HeimbergerDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-9970-8695

Funding

CARCINOGENESIS TRAINING PROGRAMT32CA009560 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Kathleen Janee Green · 1986 to 2026
$8.4M
NCI NIH HHS T32 CA009560
6 · The paper itself

Abstract

Survivin (

Indexed as

Antineoplastic AgentsNeoplasmsSurvivinAnimalsApoptosisDrug Resistance, NeoplasmHumansMolecular Targeted TherapyAntineoplastic AgentsBIRC5 protein, humanSurvivinapoptosisbreast cancerglioblastomasurvivin

Identifiers

PMID41373575
PMCPMC12692146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.