Evidence map›Paper›PMID 41373511›Full record

ArticleInternational journal of molecular sciences2025

A Comparative Metabolomics Study of Multiple Urological Diseases by Highly Sensitive Dansylation Isotope Labeling LC-MS.

Wei-Hsuan Wang, Ya-Ju Hsieh, Chien-Lun Chen, Ying-Hsu Chang, Yi-Huai Tsai, Chih-Hsiang Chang, Liang Li, Wei-Ju Tu, Jau-Song Yu, Yi-Ting Chen

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei-Hsuan WangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Ya-Ju HsiehMolecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-3853-4342
Chien-Lun ChenDepartment of Urology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-0322-4072
Ying-Hsu ChangCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yi-Huai TsaiMolecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chih-Hsiang ChangKidney Research Center, Department of Nephrology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.ORCID 0000-0002-7342-335X
Liang LiDepartment of Chemistry, University of Alberta, Edmonton, AB T6G2G2, Canada.ORCID 0000-0002-9347-2108
Wei-Ju TuGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Jau-Song YuMolecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-4295-983X
Yi-Ting ChenMolecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-0063-4965

Funding

the Chang Gung Memorial Hospital, Taiwan CORPD1P0061 and BMRPD78the Ministry of Science and Technology, Taiwan NSTC 113-2113-M-182-001, 113-2314-B-182-026-MY2, 110-2813-C-182-004-M, 112-2813-C-182-065-M, 114-2113-M-007-024, 114-2622-M-182-001 and 114-2113-M-182-002the proteomic core lab at Molecular Medicine Research Center of Chang Gung University, Taoyuan, Taiwan CLRPD1J0016
6 · The paper itself

Abstract

Urine analysis is a straightforward, non-invasive testing method that, when integrated with metabolomics, shows great potential for detecting small-molecule metabolites as biomarkers of abnormal metabolic activity in the urinary tract, including drug interactions, toxicity, and diseases. However, integrated and comparative analyses of multiple urinary tract pathologies are currently limited. In this study,

Indexed as

Dansyl CompoundsIsotope LabelingMetabolomicsUrologic DiseasesAdultAgedBiomarkersChromatography, LiquidHumansLiquid Chromatography-Mass SpectrometryMaleMetabolomeMiddle AgedProstatic HyperplasiaProstatic NeoplasmsTandem Mass SpectrometryBiomarkersdansyl chlorideDansyl Compoundsisotope labeling LC-MSmetabolomicsurinary metabolomeurinary tract diseases

Identifiers

PMID41373511
PMCPMC12691989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.