ArticleInternational journal of molecular sciences2025
The N-Terminal Domain of Tailspike Depolymerases Affects the Replication Efficiency of Synthetic
Ivan K Baykov, Ekaterina E Mikhaylova, Anna V Miroshnikova, Valeriya A Fedorets, Sofya A Markova, Tatyana A Ushakova, Vera V Morozova, Nina V Tikunova
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In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
8 authors.
Ivan K BaykovLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Ekaterina E MikhaylovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Anna V MiroshnikovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Valeriya A FedoretsLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0009-0000-2070-6332 Sofya A MarkovaFaculty of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia.
Tatyana A UshakovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Vera V MorozovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Nina V TikunovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Funding
Russian Science Foundation 24-24-00553
6 · The paper itselfAbstract
Bacteriophage receptor-binding proteins are often attached to the tail via a conserved N-terminal adapter/anchor domain, presumed to function independently from the distal receptor-binding/catalytic domain. Using synthetic phage technology, we demonstrated that the N-terminal domain in
Indexed as
BacteriophagesKlebsiellaViral Tail ProteinsVirus ReplicationGlycoside HydrolasesProtein BindingProtein DomainsGlycoside Hydrolasestailspike protein, bacteriophageViral Tail Proteinsadapter domainanchor domainbacteriophagegenome assemblyKlebsiellareceptor-binding proteinsynthetic biologytailspike depolymerasetransformation-associated recombination cloning
Identifiers
PMID41373458
PMCPMC12692247
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