Evidence map›Paper›PMID 41373458›Full record

ArticleInternational journal of molecular sciences2025

The N-Terminal Domain of Tailspike Depolymerases Affects the Replication Efficiency of Synthetic

Ivan K Baykov, Ekaterina E Mikhaylova, Anna V Miroshnikova, Valeriya A Fedorets, Sofya A Markova, Tatyana A Ushakova, Vera V Morozova, Nina V Tikunova

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivan K BaykovLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Ekaterina E MikhaylovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Anna V MiroshnikovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Valeriya A FedoretsLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0009-0000-2070-6332
Sofya A MarkovaFaculty of Natural Sciences, Novosibirsk State University, Novosibirsk 630090, Russia.
Tatyana A UshakovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Vera V MorozovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Nina V TikunovaLaboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.

Funding

Russian Science Foundation 24-24-00553
6 · The paper itself

Abstract

Bacteriophage receptor-binding proteins are often attached to the tail via a conserved N-terminal adapter/anchor domain, presumed to function independently from the distal receptor-binding/catalytic domain. Using synthetic phage technology, we demonstrated that the N-terminal domain in

Indexed as

BacteriophagesKlebsiellaViral Tail ProteinsVirus ReplicationGlycoside HydrolasesProtein BindingProtein DomainsGlycoside Hydrolasestailspike protein, bacteriophageViral Tail Proteinsadapter domainanchor domainbacteriophagegenome assemblyKlebsiellareceptor-binding proteinsynthetic biologytailspike depolymerasetransformation-associated recombination cloning

Identifiers

PMID41373458
PMCPMC12692247

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.