Evidence map›Paper›PMID 41373330›Full record

ArticleHealthcare (Basel, Switzerland)2025

Effect of Moderate-to-High-Intensity Interval Aerobic Exercise on Clinical Symptoms During the Menstrual Cycle: A Pilot Randomized Controlled Trial.

Alejandra Pio-Soria, Doaa Zahran, Alberto Roldán-Ruiz

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alejandra Pio-SoriaDepartamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain.
Doaa ZahranDepartamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain.
Alberto Roldán-RuizDepartamento de Fisioterapia, Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Ctra. Pozuelo-Majadahonda Km 1,800, Pozuelo de Alarcón, 28223 Madrid, Spain.ORCID 0009-0001-1950-2778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrimary dysmenorrhea is one of the most prevalent gynecological disorders. It has been shown to negatively impact quality of life and overall wellbeing, as recent studies have associated stress and physical inactivity with both the onset and severity of menstrual pain.

objectiveTo analyze the effectiveness of a moderate-to-high-intensity interval aerobic exercise on menstrual pain intensity, menstrual-related quality of life, general health-related quality of life, sleep quality, stress and anxiety, and drug intake in young women with primary dysmenorrhea. METHODOLOGY: A total of 20 women were randomly allocated to either the exercise (N = 10) or control group (N = 10). Primary outcomes were menstrual pain intensity and menstrual-related quality of life. Secondary outcomes included general health-related quality of life, sleep quality, stress and anxiety, and drug intake. A supervised moderate-to-high-intensity interval aerobic exercise program on a stationary bicycle was carried out twice a week, for eight weeks, in young women with regular cycles and no diagnosed medical conditions. Patients were assessed at baseline, and at 1- and 2-month follow-ups.

resultsAt 8 weeks, 17 women completed the follow-up. Analyses showed statistically significant differences in favor of moderate-to-high-intensity interval aerobic exercise at 2-month follow-up for menstrual pain intensity, with a large size effect. Significant changes were also found in menstrual-related quality of life at both follow-ups in the exercise group, but they were not superior to the control group. No significant changes were observed for the rest of the variables in either group.

conclusionsThe results from this pilot study suggest that the moderate-to-high-intensity interval aerobic exercise program is effective in reducing menstrual pain intensity at 2-month follow-ups. Future randomized controlled trials with larger samples are required to confirm the results.

Indexed as

aerobic exercisemenstrual painprimary dysmenorrheaquality of lifesleep qualitystress

Identifiers

PMID41373330
PMCPMC12692201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.