Evidence map›Paper›PMID 41373314›Full record

ArticleHealthcare (Basel, Switzerland)2025

MetaAcuPoint: MetaHuman-Generated Synthetic Data for Hand Acupoint Localization.

Kasunika Guruge, Prathiksha Padmanabha, H M K K M B Herath, Nuwan Madusanka, Hi-Joon Park, Chang-Su Na, Myunggi Yi, Byeong-Il Lee

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kasunika GurugeIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0001-6641-9320
Prathiksha PadmanabhaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0009-0009-6758-9677
H M K K M B HerathIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-1873-768X
Nuwan MadusankaDigital Healthcare Research Center, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0001-7982-1036
Hi-Joon ParkCollege of Korean Medicine, Kyung Hee University, Seoul 02453, Republic of Korea.ORCID 0000-0002-0538-2664
Chang-Su NaCollege of Korean Medicine, Dongshin University, Jeonnam 58245, Republic of Korea.ORCID 0000-0001-5478-649X
Myunggi YiIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0003-4864-959X
Byeong-Il LeeIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-1574-7145

Funding

National Research Foundation of Korea (NRF) and the Ministry of Science and ICT. 2022M3A9B6082791
6 · The paper itself

Abstract

backgroundPrecise localization of acupuncture points (acupoints) is crucial for the clinical success of Traditional Korean Medicine (TKM). Traditional methods that rely on visual inspection and palpation are subjective and prone to inter- and intra-observer differences, making standardization challenging. The progress of data-driven localization techniques is also limited by the scarcity of annotated datasets and inconsistent labeling quality.

objectiveThis study presents MetaAcuPoint, a synthetic dataset created to overcome these limitations by providing high-fidelity, anatomically consistent hand images for acupoint localization.

methodsMetaAcuPoint was generated using MetaHuman avatars within Unreal Engine, resulting in 900 RGB hand images. Anatomically aligned, bone-attached sockets were implemented for five diagnostically relevant hand acupoints, ensuring millimeter-level precision and spatial consistency across various hand poses. Dataset validity was assessed by training a high-resolution network (HRNet-W48) within the MMPose framework and testing its performance on real-world forearm images.

resultsThe synthetic-trained model achieved a mean distance error (MDE) of 5.67 ± 3.13 pixels, closely aligning with the real-data baseline at 4.81 ± 2.85 pixels. Adding synthetic samples to real data further enhanced performance (MDE: 4.95 pixels). In contrast, manually annotated synthetic images yielded poorer results (MDE: 12.76 pixels), emphasizing the advantages of automated anatomical annotation. Generalization tests across four external datasets confirmed that the synthetic data-trained model outperformed the real-data-trained model, maintaining higher accuracy (MDE: 5.84-6.45 mm vs. 10.63-15.80 mm).

conclusionsMetaAcuPoint demonstrates the first example of synthetic-to-real generalization for hand acupoint localization. By combining photorealistic rendering with anatomically grounded annotation, the dataset offers a reliable resource to promote standardized, data-driven approaches in acupuncture research and practice.

Indexed as

acupoint localizationannotation consistencydeep learningMetaHumansynthetic datavirtual reality

Identifiers

PMID41373314
PMCPMC12691809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.