Evidence map›Paper›PMID 41373167›Full record

ReviewThe plant genome2025

Benefits, concerns, and sustainable alternatives to genetically modified crops from a global and Indian perspective.

Chittaranjan Kole, Sarita Pandey, Jeshima Khan Yasin, Sujan Mamidi, Abhishek Bohra, Poulami Bhattacharya, Devraj Dhanraj, Gnanasekaran Madhavan, Dinesh Saini, Sayak Ganguli and 10 more

Abstract readReview
In one paragraph

Review in The plant genome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Chittaranjan KoleTagore Society for Rural Development, Kolkatta, India.
Sarita PandeySchool of Agriculture and Allied Sciences, The Neotia University, Sarisha, West Bengal, India.ORCID https://orcid.org/0000-0002-6392-9904
Jeshima Khan YasinDivision of Genomic Resources, National Bureau of Plant Genetic Resources, New Delhi, India.ORCID https://orcid.org/0000-0003-4932-3866
Sujan MamidiHudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA.ORCID https://orcid.org/0000-0002-3837-6121
Abhishek BohraICAR-Indian Institute of Pulses Research (IIPR), Kanpur, India.ORCID https://orcid.org/0000-0003-4569-8900
Poulami BhattacharyaGenetics and Plant Breeding, The Neotia University, Sarisha, West Bengal, India.
Devraj DhanrajThe Graduate School, ICAR-Indian Agricultural Research Institute, New Delhi, India.ORCID https://orcid.org/0009-0005-2037-7301
Gnanasekaran MadhavanDepartment of Agronomy, Tamil Nadu Agricultural University, Coimbatore, India.ORCID https://orcid.org/0009-0001-4681-2579
Dinesh SainiDepartment of Plant and Soil Science, Texas Tech University, Lubbock, Texas, USA.ORCID https://orcid.org/0000-0002-6347-6183
Sayak GanguliPostgraduate and Research Department of Biotechnology, St. Xavier's College (Autonomous), Kolkata, India.
Bhargavi HaDivision of Vegetable Crops, ICAR-Indian Institute of Horticultural Research, Bengaluru, India.
Sayanti MandalDepartment of Chemistry and Biochemistry, Sharda School of Basic Sciences & Research, Sharda University, Greater Noida, India.
Sangita AgarwalDepartment of Applied Science, RCC Institute of Information Technology, Kolkata, India.
Arumugam Pillai MDepartment of Plant Breeding and Genetics, Agricultural College and, Research Institute, Tamil Nadu Agricultural University, Killikulam, India.
Madhugiri Nageswara-RaoUSDA-ARS-Subtropical Horticulture Research Station, Miami, Florida, USA.
Swarup K ChakrabartiICAR-CPRI, Shimla, Kolkata, India.
Prakash C SharmaUniversity School of Biotechnology, Guru Gobind Singh Indraprastha University, New Delhi, India.
Akshay TalukdarGenetics Division, ICAR-Indian Agricultural Research Institute, Pusa, New Delhi, India.
Jogeswar PanigrahiPG Department of Biotechnology, Berhampur University, Berhampur, India.
Manikanda Boopathi NDepartment of Plant Biotechnology, Center for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore, India.ORCID https://orcid.org/0000-0003-3615-3386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global population, set to exceed 10 billion by 2050, presents enormous challenges to food, health, nutrition, energy, and environmental security. Plant breeding methods have continuously evolved to develop improved crop varieties to meet these demands. Among the recent developments, genetically modified crops (GMCs) have emerged as a viable option to enhance crop yields, nutritional value, biofuel potential, and climatic adaptability. However, extensive application of GMCs is a very controversial subject due to biosafety issues, environmental impacts, economic viability, and legal considerations. This review presents a critical evaluation of the merits and limitations of GMCs, along with a discussion of available alternative approaches, with particular reference to the Indian context. While GMCs have been developed with increased yields, improved shelf life, reduced pesticide and herbicide use, and improved stress tolerance, potential risks such as health hazards and socioeconomic impacts on smallholding farmers in the developing world cannot be disregarded. Besides, regulatory policies and public perception have a significant influence on the acceptability and commercialization of GMCs, especially in countries like India. The discussion therefore encompasses other sustainable alternatives, including marker-assisted selection, genomics-aided breeding, cisgenesis, intragenesis, and stringently regulated gene editing, that embody environment-friendly approaches to agricultural enhancement. A collective assessment of these techniques is presented in order to examine their prospects for delivering long-term biosecurity without compromising environmental and human health. By integrating scientific advances, policy environments, and social perceptions, this review aims to present a balanced perspective of GMCs and their role in the future of global agriculture, particularly in the Global South.

Indexed as

Crops, AgriculturalPlants, Genetically ModifiedGene EditingIndiaPlant Breeding

Identifiers

PMID41373167
PMCPMC12696234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.