Evidence map›Paper›PMID 41373109›Full record

ReviewCurrent opinion in urology2026

Modern integrative prostate cancer diagnostics.

Rainer Grobholz, Felice Burn, Lukas Prause

Abstract readReview
In one paragraph

Review in Current opinion in urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rainer GrobholzMedical Faculty, University of Zurich, Zurich.
Felice BurnInstitute of Radiology.
Lukas PrauseDepartment of Urology, Kantonsspital Aarau, Aarau, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo review contemporary applications, performance, and implementation challenges of artificial intelligence (AI) in the radiological and pathological diagnosis of prostate cancer, and to highlight emerging multimodal AI biomarkers for prognosis and treatment selection. RECENT

findingsIn radiology, large multicenter studies demonstrate that MRI-based AI can detect clinically significant prostate cancer with accuracy comparable to, and in some contexts surpassing, expert radiologists, while reducing inter-reader variability and improving workflow efficiency. In surgical pathology, AI systems show high concordance with pathologists in cancer detection and Gleason grading, helping standardize challenging features such as Gleason pattern 4 and supporting triage or second-reader workflows. However, emerging transformative potential lies in multimodal AI systems that integrate digital histopathology with clinical and molecular data to deliver prognostic and predictive biomarkers. These tools are now being validated in randomized trials and real-world cohorts and are beginning to be recognized in clinical guidelines. SUMMARY: AI is a powerful assistive technology that can enhance diagnostic accuracy, reproducibility, and efficiency across MRI and pathology. The integration of multimodal data is catalyzing validated biomarkers to guide risk stratification and treatment decisions - the next frontier in personalized prostate cancer care. But broad adoption still requires rigorous external validation, quality assurance, and ongoing postdeployment monitoring.

Indexed as

Artificial IntelligenceMagnetic Resonance ImagingProstateProstatic NeoplasmsBiomarkers, TumorHumansMaleNeoplasm GradingPrognosisReproducibility of ResultsBiomarkers, Tumorartificial intelligenceartificial intelligence biomarkerdigital pathologymagnetic resonance imagingprostate cancer

Identifiers

PMID41373109
PMCPMC12893158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.