Evidence map›Paper›PMID 41373075›Full record

ArticleAnnals of medicine2025

A comparison of allied healthcare versus no allied healthcare on participation, fatigue, physical functioning and health-related quality of life for patients with persistent complaints after a COVID-19 infection.

Ângela Jornada Ben, Anita Natalia Varga, Siméon de Bruijn, Willem Bastiaan Dekker, Cees C van den Wijngaard, Arie Cornelis Verburg, Thomas Johannes Hoogeboom, Philip van der Wees, Raymond W J G Ostelo, Judith E Bosmans and 1 more

Abstract readComparative Study
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Ângela Jornada BenDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.ORCID 0000-0003-4793-9026
Anita Natalia VargaDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.ORCID 0000-0001-8185-5227
Siméon de BruijnCenter for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.ORCID 0009-0000-6878-6298
Willem Bastiaan DekkerDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.
Cees C van den WijngaardCenter for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.ORCID 0000-0003-4309-0694
Arie Cornelis VerburgIQ Health science department, Radboud university medical center, Nijmegen, the Netherlands.ORCID 0000-0003-4068-8228
Thomas Johannes HoogeboomIQ Health science department, Radboud university medical center, Nijmegen, the Netherlands.ORCID 0000-0003-2103-419X
Philip van der WeesIQ Health science department, Radboud university medical center, Nijmegen, the Netherlands.ORCID 0000-0003-2881-5159
Raymond W J G OsteloDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.ORCID 0000-0001-7679-7210
Judith E BosmansDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.ORCID 0000-0002-1443-1026
Johanna Maria van DongenDepartment of Health Sciences, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, the Netherlands.ORCID 0000-0002-1606-8742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effectiveness of allied healthcare MATERIALS AND

methodsData from the ParaCOV cohort (allied healthcare,

resultsPatients receiving allied healthcare were older (49.2 vs. 41.2 years), less often female (63.3% vs. 70.1%), had higher BMI (28.2 vs. 26.1), smoked less frequently (5.0% vs. 9.0%), had more comorbidities (49.2% vs. 41.9%), and lower baseline anxiety and depression scores compared to those not receiving allied healthcare. For participation, ATEs after 6 and 12 months were respectively -2.62 (95%CI: -4.39; -0.86) and -1.68 (95%CI: -4.81;1.45), with BTGDs of 4.7% and 1.8% favoring the control. For fatigue, ATEs were 1.72 (95%CI: -0.14; 3.58) and 0.97 (95%CI: -1.48; 3.41), with BTGDs of 6.5% and 3.7% favoring the control. For physical functioning, ATEs were 5.75 (95% CI: 4.42; 7.09) and 6.36 (95%CI: 4.84; 7.88), with BTGDs of 1.4% and 2.2% favoring allied healthcare. For health-related quality of life, ATEs were 0.017 (95%CI: -0.008; 0.0044) and 0.033 (95%CI: 0.011; 0.054).

conclusionsPatients with persistent complaints after a COVID-19 infection showed significantly lower participation after 6 months, higher health-related quality of life after 12 months, and better physical functioning after 6 and 12 months of allied healthcare, however, BTGDs were not clinically relevant. Study limitations warrant cautious results interpretation.

Indexed as

COVID-19FatigueQuality of LifeAdultAgedAnxietyComorbidityFemaleHumansMaleMiddle AgedSARS-CoV-2allied healthcarehealth-related quality of lifeLong COVIDparticipationphysical functioningrehabilitation

Identifiers

PMID41373075
PMCPMC12720634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.