Evidence map›Paper›PMID 41372945›Full record

ArticleBMC health services research2025

Provider perceptions and experiences integrating depression treatment into chronic healthcare services in Neno District, Malawi: a qualitative study.

Myrrah Kamwiyo, Owen Mwale, Kondwani Mpinga, Waste Kayira, Ian Johnson, Todd Ruderman, Beatrice Matanje, Karen Kasambara, Amruta Houde, Rachel Isaacs and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04777006 (Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04777006 phase4completednot on this map

Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform

TypeinterventionalSponsorRANDRan2021 to 2025Enrolled487ConditionsDepressive DisorderArmsProblem Management Plus, Antidepressant Therapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Myrrah KamwiyoPartners in Health, Neno, Malawi.
Owen MwalePartners in Health, Neno, Malawi.
Kondwani MpingaPartners in Health, Neno, Malawi.
Waste KayiraPartners in Health, Neno, Malawi.
Ian JohnsonUnion College, Lincoln, NE, USA.
Todd RudermanPartners in Health, Neno, Malawi.
Beatrice MatanjePartners in Health, Neno, Malawi.
Karen KasambaraPartners in Health, Neno, Malawi.
Amruta HoudePartners in Health, Boston, MA, USA.
Rachel IsaacsPartners in Health, Boston, MA, USA.
Cecilia NeedhamHarvard Medical School, 20 Park Plz, Boston, MA, 02116, USA.
Glenn WagnerRAND, Santa Monica, CA, USA.
Kazione KulisewaKamuzu University of Health Sciences, Blantyre, Malawi.
Michael UdediMinistry of Health, Lilongwe, Malawi.
Ryan K McBainHarvard Medical School, 20 Park Plz, Boston, MA, 02116, USA. rmcbain@rand.org.ORCID http://orcid.org/0000-0003-0073-0348

Funding

Integrating a Stepped Care Model of Screening and Treatment for Depression into Malawi's National HIV Care Delivery PlatformR01MH117760 · NIMH · RAND CORPORATION · PI MCBAIN, RYAN K, WAGNER, GLENN JOHN · 2020 to 2024
$3.0M
NIMH NIH HHS R01 MH117760
6 · The paper itself

Abstract

backgroundIn low-resource settings, integrating mental health services into existing care platforms is critical to expanding access and improving quality of care. In Neno District, Malawi, the Integrated Chronic Care Clinic–Depression module (IC3D) clinical trial introduced depression screening and treatment, including antidepressant therapy (ADT) and group Problem Management Plus (PM+), within chronic care services. This study explored healthcare and lay providers’ experiences and perceptions of integrating depression care for patients with chronic conditions at these clinics.

methodsWe conducted an exploratory qualitative study using semi-structured key informant interviews with 18 depression care providers (eight clinical officers and ten counselors). Interviews were transcribed, translated from Chichewa to English, and analyzed thematically using Dedoose 9.0 to identify patterns in these providers’ perceptions of effectiveness, facilitators, barriers, and recommendations for care integration.

resultsFour key themes emerged from the interviews. First, providers reported positive perceptions of intervention effectiveness, noting improvements in patients’ mental, physical, and functional health, including blood pressure control and HIV viral suppression. Second, providers shared constructive feedback on elements of intervention facilitation, including the PM + user guide, group format, and ongoing training and mentorship. Third, providers identified key challenges which included transportation barriers, increased workload, and missed appointments. Finally, providers recommended ways to improve care delivery, such as allocating additional resources as well as expanding infrastructure and depression screening at additional patient entry points such as outpatient departments and palliative care.

conclusionsBased on provider testimony, the integration of depression care into chronic care services in Neno District, Malawi is perceived as feasible, acceptable, and impactful. Their insights underscore the value of structured mentorship, task-shifting, and holistic care approaches in low-resource settings. These findings will be used to inform government-led district-wide strategies and policy for strengthening behavioral and pharmacologic treatment of depression in Neno District, including recommendations to address logistical constraints, ensure consistent supervision and documentation, and expand screening access. Future research should explore strategies to improve the integrated depression model, including accounting for comorbid mental health conditions, and expanding access to screening and care.

trial registrationThe trial was registered with Clinical Trials. Gov: NCT04777006 (Registration Date: February 23, 2021).

Indexed as

Attitude of Health PersonnelDelivery of Health Care, IntegratedDepressionMental Health ServicesAdultAntidepressive AgentsChronic DiseaseFemaleHumansInterviews as TopicMalawiMaleQualitative ResearchResource-Limited SettingsAntidepressive AgentsAntidepressant therapyIntegrated chronic care clinicsNon-communicable diseasesProblem management plus

Identifiers

PMID41372945
PMCPMC12801780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.