Evidence map›Paper›PMID 41372857›Full record

ArticleBMC endocrine disorders2025

Association between dietary amino acids ratio with metabolic profile and C-Peptide levels among overweight individuals.

Saade Abdalkareem Jasim, Enwa Felix Oghenemaro, Mohammed Yousif Merza, Lalji Baldaniya, Subbulakshmi Ganesan, Muath Suliman, Zafar Aminov, Amritesh Nagarwal, Abed J Kadhim, Munthar Kadhim

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Article in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Saade Abdalkareem JasimMedical Laboratory Techniques Department, College of Health and Medical Technology, University of Al-maarif, Anbar, Iraq. abdalkareemjasimsaade@gmail.com.
Enwa Felix OghenemaroDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Delta State University, PMB 1, Abraka, Delta State, Nigeria. felixoghenemaroenwa@gmail.com.
Mohammed Yousif MerzaClinical Analysis Department, Hawler Medical University, Erbil, Iraq.
Lalji BaldaniyaDepartment of Pharmacy, Faculty of Health Sciences, Marwadi University Research Center, Marwadi University, Rajkot, Gujarat, 360003, India.
Subbulakshmi GanesanDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
Muath SulimanCentral Labs, King Khalid University, P.O. Box 960, AlQura'a, Abha, Saudi Arabia.
Zafar AminovDepartment of Public Health and Healthcare Management, Samarkand State Medical University, 18 Amir Temur Street, Samarkand, Uzbekistan.
Amritesh NagarwalDepartment of Cardiology, National Institute of Medical Sciences, NIMS University Rajasthan, Jaipur, India.
Abed J KadhimDepartment of Medical Engineering/Al-Nisour University College, Baghdad, Iraq.
Munthar KadhimCollege of Pharmacy, The Islamic University, Najaf, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeing overweight is a growing concern worldwide, characterized by a body mass index (BMI) ranging from 25 to 29.9 kg/m

methodsA total of 221 overweight participants were enrolled in this study. Dietary intake was assessed using a validated food frequency questionnaire (FFQ). We conducted laboratory tests to measure metabolic variables, lipid profiles, glycemic indicators, and C-Peptide levels.

resultsParticipants in the highest tertile of the dietary BCAAs/AAAs ratio exhibited significantly lower blood sugar levels and higher concentrations of high-density lipoprotein (HDL) compared to those in the lowest tertiles, with p-values of 0.033 and 0.003, respectively.

conclusionOur findings suggest that a higher dietary ratio of BCAAs to AAAs is linked to improved metabolic health among overweight individuals. However, further longitudinal studies are necessary to clarify the causal relationships between these dietary factors and metabolic outcomes. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Amino AcidsAmino Acids, AromaticAmino Acids, Branched-ChainBiomarkersC-PeptideDietMetabolomeOverweightAdultBody Mass IndexFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisAmino AcidsAmino Acids, AromaticAmino Acids, Branched-ChainBiomarkersC-PeptideAromatic amino acidsBranched chain amino acidsC-PeptideOverweight

Identifiers

PMID41372857
PMCPMC12801902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.