Trial reportBMC anesthesiology2025
Comparative efficacy of modified nasopharyngeal airway and nasal cannula for oxygenation in deeply sedated patients undergoing endoscopic retrograde cholangiopancreatography: a randomized controlled trial.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Safety and Efficacy of Remimazolam Combined with Esketamine for Anesthesia in Elderly Patients Undergoing ERCP: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Establishing the Median Effective Dose of Tegileridine for Immediate Postoperative Analgesia Following Laparoscopic Colorectal Cancer Surgery: A Sequential Dose-Finding Study.Drug design, development and therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundHypoxemia frequently occurs during deeply sedated endoscopic retrograde cholangiopancreatography (ERCP). Modified nasopharyngeal airway (mNPA) is a nasopharyngeal cannula with a ventilation adapter connected to an anesthesia circuit for respiratory support. This single-blind, two-group, randomized controlled trial aimed to evaluate the efficacy and safety of mNPA relative to nasal cannula (NC) in patients undergoing ERCP sedation.
methodsAdult participants scheduled for elective ERCP under sedation were randomly assigned in a 1:1 ratio to receive either mNPA or NC for oxygen supply. Both groups were administered 1.5 to 2.0 mg/kg intravenous propofol and 5 to 10 µg sufentanil. The primary outcome was hypoxemia (SpO
resultsIn total, 596 patients were enrolled without dropouts or missing data. Those receiving mNPA (N = 295) had a significantly lower incidence of hypoxemia than those receiving NC oxygen supply (N = 301; 7.1% vs. 13.6%, P = 0.009). The incidence of SpO
conclusionsThe utilization of mNPA for oxygen delivery during ERCP sedation led to a marked decrease in hypoxemia incidence and associated procedural disruptions. These finding offer valuable insights for airway management during deep sedation for ERCP anesthesia management and warrant consideration in clinical practice.
trial registrationChictr.org.cn ChiCTR2300075730 (date of registration: September 14, 2023).
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