Evidence map›Paper›PMID 41372801›Full record

Trial reportEuropean journal of medical research2025

A study of post-urination external genital cleansing behavior and its impact on improving dapagliflozin adherence in Chinese male heart failure patients.

Xiaorong Yuan, Tao Liu, Xiaoyu Zhang, Chunyan He, Shifang Xiao, Hong Xiao, Hua Liu, Bin Zhu

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaorong YuanDepartment of Cardiovascular Medicine,Luzhou Hospital of Traditional Chinese Medicine, Southwest Medical University, No. 11, Jiangyang South Road, Jiangyang District, Luzhou, 646000, Sichuan Province, China.
Tao LiuDepartment of Cardiovascular Medicine, Wuhan Red Cross Hospital, 392 Hong Kong Road, Jianghan District, Wuhan, 430015, Hubei, China.
Xiaoyu ZhangDepartment of Medicine, Suining Central Hospital, 127 Desheng West Road, Funshan District, Suining, 629000, Sichuan, China.
Chunyan HeDepartment of Internal Medicine, Lu County Hospital of Traditional Chinese Medicine, Jinxiu Road, Yunjin Town, Luzhou, 646102, Sichuan, China.
Shifang XiaoDepartment of Cardiovascular and Cerebrovascular Medicine, Naxi District Hospital of Traditional Chinese Medicine, No. 22, Section 1, Yunxi Road, Anfu Street, Naxi District, Luzhou, 646300, Sichuan, China.
Hong XiaoDepartment of Internal Medicine, The Second People's Hospital of Naxi District, 168 Yongning Street, Guiguo Town, Naxi District, Luzhou, 646300, Sichuan, China.
Hua LiuSchool of Bioscience and Technology, Chengdu Medical College, Chengdu, 610050, Sichuan, China.
Bin ZhuDepartment of Cardiovascular Medicine,Luzhou Hospital of Traditional Chinese Medicine, Southwest Medical University, No. 11, Jiangyang South Road, Jiangyang District, Luzhou, 646000, Sichuan Province, China. lzlinzhiqiu@163.com.

Funding

the Luzhou City Hospital of Traditional Chinese Medicine-Southwest Medical University Strategic Cooperative Research Project 2022SZYXNYD02
6 · The paper itself

Abstract

backgroundWhile the relationship between genital hygiene practices and infection risk has been well-documented in various clinical settings, limited attention has been paid to preventive strategies specifically targeting male heart failure patients on dapagliflozin. This study aims to evaluate the impact of post-urination external genital cleaning on dapagliflozin medication adherence in male heart failure patients. METHODS AND

resultsA multicenter, randomized, single-blind, parallel-controlled study was conducted with 1337 male heart failure patients on dapagliflozin therapy. The test group performed simple external genital cleaning post-urination, while the control group maintained routine care. Primary outcomes included genital fungal infection incidence, medication-related concerns, belief intensity, and medication adherence, assessed over a 1-year period. The test group demonstrated significantly lower rates of genital fungal infections compared to controls (0.75% vs. 3.14%, P = 0.002). Additionally, the test group showed higher dapagliflozin adherence rates (72.75% vs. 63.23%, P < 0.001).

conclusionPost-urination external genital cleaning significantly improves dapagliflozin medication adherence in male heart failure patients.

Indexed as

Benzhydryl CompoundsGlucosidesHeart FailureMedication AdherenceSodium-Glucose Transporter 2 InhibitorsAgedChinaEast Asian PeopleHumansMaleMiddle AgedSingle-Blind MethodBenzhydryl CompoundsdapagliflozinGlucosidesSodium-Glucose Transporter 2 InhibitorsDapagliflozinExternal genital cleansing behaviourMale heart failure patientsMedication adherence

Identifiers

PMID41372801
PMCPMC12802190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.