ArticleCommunications medicine2025
Productivity-adjusted life year loss among the late middle-aged adults in China.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Association Between Health-Related Quality of Life In Patients with Colorectal Cancer and Their Informal Caregivers.Advances in therapy · 2026Article
- Diverging Incidence and Mortality of Cutaneous Melanoma in Mainland China, 1990-2023, with Projections to 2030: A Global Burden of Disease 2023 Analysis.Clinical, cosmetic and investigational dermatology · 2026Article
- Productivity-adjusted life year loss among the late middle-aged adults in China.Communications medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundProductivity-adjusted life years (PALYs) measure the impact of health conditions on an individual's ability to contribute productively to the economy. However, they have not been evaluated for the Chinese population. We aim to estimate PALYs for the Chinese population aged 50 to 64 years.
methodsWe applied the China Aging and Retirement Simulation (CHARISMA) model, a validated microsimulation model, to calculate PALYs for three age cohorts (50-54, 55-59, 60-64). PALYs were calculated by integrating workforce participation, absenteeism, and death. A probabilistic sensitivity analysis was conducted to address parameter uncertainties. PALY losses due to specific conditions were estimated by nullifying each health condition's risk separately. The results were stratified by sociodemographic factors and adjusted using 2018 population data to estimate total PALYs accrued by 2032.
resultsHere we show that the average PALYs before age 65 are 6.80, 4.35, and 1.50 years for the 50-54, 55-59, and 60-64 age groups, respectively. Significant PALY variations are observed among subgroups, with males, rural residents, and individuals with lower education exhibiting higher PALYs. From 2018 to 2032, total accrued PALYs for the cohort initially aged 50-64 in 2018 are approximately 1.24 billion years. The primary conditions contributing to PALY loss are dyslipidemia, hypertension, heart disease, diabetes, and stroke.
conclusionsThis study reveals substantial sociodemographic variations in PALYs and identifies major health conditions impacting productivity. Our results can guide targeted health interventions and policies to sustain workforce productivity and social security amid China's aging demographics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.