ArticleJournal of robotic surgery2025
Study - International multicentric minimally invasive liver resection (SIMMILR-4) : a comparison of conventional, digitally enhanced and collaborative robotic with Tele-robotic laparoscopic surgery for colorectal liver metastases.
Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This international multicenter study compared five surgical approaches for resection of colorectal liver metastases (CRLM): open, conventional laparoscopy (L), digitally enhanced laparoscopy with 3D imaging (DEL), collaborative robotic laparoscopy with a single robotic arm (CRL) with tele-robotic laparoscopic surgery with 3D imaging and 4 robotic arms (TRL). This exploratory study aimed to assess whether TRL liver resection for colorectal liver metastases (CRLMs) demonstrates potential advantages over conventional laparoscopy (L), digitally enhanced laparoscopy (DEL), or collaborative robotic laparoscopy (CRL). A retrospective analysis of 1,257 patients undergoing CRLM resection across five centers was performed. Surgical techniques were classified as O, L, DEL, CRL, or TRL. Because of limited case numbers in the DEL, CRL, and TRL groups, the primary comparison was between all minimally invasive surgery (MIS) cases combined (L, DEL, CRL, TRL; n = 283) and matched open controls (n = 283) using 1:1 propensity score matching. Outcomes included estimated blood loss (EBL), operative time, length of stay (LOS), resection margin status (R0), and major complications (Clavien-Dindo grade ≥ 3). MIS demonstrated significantly lower EBL (505 mL vs. 692 mL, p < 0.0001) and shorter LOS (8 vs. 14 days, p < 0.0001) compared with open surgery. Subgroup analyses of DEL, CRL, and TRL (each < 21 patients post-match) showed comparable perioperative outcomes, suggesting incremental adoption of advanced technologies did not compromise safety or efficiency. MIS offers significant reductions in blood loss and hospital stay compared with open surgery. While TRL provides technical advantages, it did not show clear superiority. Prospective standardized multicenter studies are needed to confirm these exploratory findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.