Evidence map›Paper›PMID 41372540›Full record

ArticleEye (London, England)2026

Analysis of the impact of FS-LASIK on peripheral retinal defocus and its influencing factors in myopic adults.

Yu Li, Chen Yang, Bo Mei, Dan Su, Yi Yue, Yue-Hua Zhou

Abstract read
In one paragraph

Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu Li *Eye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.ORCID 0009-0009-2124-6716
Chen Yang *Eye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Bo MeiEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Dan SuEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Yi YueEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Yue-Hua ZhouEye School of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China. zhou_yh2025@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the retinal peripheral defocus changes following femtosecond laser in situ-keratomileusis (FS-LASIK) in myopic adults and analyse influencing factors.

methodsThis study recruited 202 patients who underwent FS-LASIK with myopia at Beijing Ming Vision Eye Hospital. Participants were divided into low myopia (LM, -0.50D to -3.00D), moderate myopia (MM, -3.00D to -6.00D), and high myopia (HM, ≥-6.00D) groups according to spherical equivalent (SE). We measured axial length (AL), total retinal defocus (TRDV), and defocus values at eccentricities ranging from 0° to 53° from the fovea, and defocus values at the superior, inferior, temporal, and nasal quadrants. With a 3-month follow-up, changes in peripheral defocus (ΔRDV) were recorded and analysed.

resultsNo significant differences were observed in TRDV, RDV20°-53°, and RDV-S among the three groups after surgery (all P > 0.05). RDV at 10°-53° increased with eccentricity, while all groups showed significant reductions in hyperopic defocus at 20°-53° compared to preoperative measurements (all P < 0.05). This reduction was more pronounced with severe myopia and greater eccentricity. Correlation analysis revealed that ΔRDV20°-30° and ΔRDV30°-40° positively correlated with SE and negatively correlated with AL and cutting thickness. ΔRDV40°-53° negatively correlated with AL. ΔRDV-T negatively correlated with SE, ΔRDV-N positively correlated with SE and negatively correlated with AL and cutting thickness (all P < 0.05).

conclusionFS-LASIK does not change the asymmetric distribution of RDV after surgery. It effectively reduces hyperopic defocus within the 20°-53° range around the fovea, with greater reductions noted peripherally. Higher myopia and greater cutting thickness are associated with larger defocus reductions.

Indexed as

Keratomileusis, Laser In SituLasers, ExcimerMyopiaRefraction, OcularRetinaAdultAxial Length, EyeFemaleFollow-Up StudiesHumansMaleMiddle AgedVisual AcuityYoung Adult

Identifiers

PMID41372540
PMCPMC12881515

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