ArticleScientific data2025
Proteomic Dataset of Sparganum proliferum and Spirometra mansoni to Understand Asexual Proliferation in Hosts.
Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Drug development targeting the mitochondrial respiratory chain of Sparganum proliferum: Initial biochemical and drug discovery insights into the enigmatic helminth parasite.PLoS neglected tropical diseases · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
Cestodes of the genus Spirometra are known for their complex life cycles, which involve aquatic and terrestrial hosts, with humans serving as the incidental hosts. This study presents a proteomic dataset of Sparganum proliferum and Spirometra mansoni, two medically important Spirometra group species that exhibit distinct plerocercoid developmental patterns. Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we analysed secreted proteins from the proliferative and non-proliferative plerocercoids to gain insight into the molecular basis of asexual proliferation, host-parasite interactions, and potential therapeutic targets. The dataset, which includes raw mass spectrometry files, peptide spectral matches, and protein functional annotations, is publicly available in jPOSTrepo (PXD063547 and PXD063548). This resource provides valuable data for helminth researchers investigating cestode biology and host-manipulation strategies.
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