Evidence map›Paper›PMID 41371730›Full record

ArticleBMJ open2025

Increasing the pneumonia treatment coverage among children under 5 years old through 'Enhanced Management of Pneumonia in the Community': implementation research protocol.

Humphreys Nsona, Emmanuel Golombe, Ulemu Zulu, Cathy Magombo, Haxson Twaibu, Prosper Mbemba, Chigomezgo Msowoya, Esau Chagoma, Aljanat Sadala, Clifford Dedza and 6 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Humphreys NsonaIMCI Unit, Government of Malawi Ministry of Health, Lilongwe, Central Region, Malawi.
Emmanuel GolombeKasungu District Hospital, Kasungu, Malawi.
Ulemu ZuluKasungu District Hospital, Kasungu, Malawi.
Cathy MagomboKasungu District Hospital, Kasungu, Malawi.
Haxson TwaibuIMCI Unit, Government of Malawi Ministry of Health, Lilongwe, Central Region, Malawi.
Prosper MbembaKasungu District Hospital, Kasungu, Malawi.
Chigomezgo MsowoyaKasungu District Hospital, Kasungu, Malawi.
Esau ChagomaKasungu District Hospital, Kasungu, Malawi.
Aljanat SadalaKasungu District Hospital, Kasungu, Malawi.
Clifford DedzaIMCI Unit, Government of Malawi Ministry of Health, Lilongwe, Central Region, Malawi.
Anusa MangwilisaKasungu District Hospital, Kasungu, Malawi.
Rudolf BandaKasungu District Hospital, Kasungu, Malawi.
Nyson ChizaniH and K Data Management Centre, Lilongwe, Malawi.
Whyte MpezeniKamuzu Central Hospital, Lilongwe, Central Region, Malawi.
Shamim Ahmad QaziIndependent Consultant Paediatrician, Geneva, Switzerland.
Yasir Bin NisarDepartment of Sexual, Reproductive, Maternal, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland nisary@who.int.ORCID http://orcid.org/0000-0002-9720-5699

Funding

Gates Foundation INV-008068World Health Organization 001
6 · The paper itself

Abstract

introductionPneumonia remains a leading cause of under-5 mortality in sub-Saharan Africa, accounting for approximately 14% of deaths in this age group. In Malawi, pneumonia accounts for 12% of under-5 deaths, with recent data revealing a concerning trend of over 110 000 new cases reported in 6 months. The Malawi government has made significant strides in reducing childhood mortality through the Integrated Community Case Management (iCCM) strategy, resulting in an 11% reduction in under-5 mortality over a 5-year period. However, the current iCCM strategy does not include the management of chest indrawing pneumonia in children aged 2-59 months and fast-breathing pneumonia in infants aged up to 2 months. This implementation research aims to increase pneumonia treatment coverage for under-5 year-old children in Kasungu District, Malawi, by expanding the community-based management of pneumonia by the iCCM-trained Health Surveillance Assistants (HSAs). METHODS AND ANALYSIS: The current implementation research using both qualitative and quantitative data collection methods will assess the feasibility and acceptability of iCCM-trained HSAs managing chest indrawing pneumonia and fast-breathing pneumonia in children under 5 with oral amoxicillin at the community level in district Kasungu using the existing district health system. The study will employ a district health system model, leveraging existing trained iCCM HSAs to enrol and manage infants aged 7-59 days with fast-breathing pneumonia and 2-59-month-old children with chest indrawing pneumonia in the community with 7-day and 5-day oral amoxicillin, respectively. HSAs will also use pulse oximetry to identify hypoxaemic children for prompt referral to a hospital for further care. Sociodemographic features of enrolled children will be documented. Enrolled children will be followed up on treatment compliance using follow-up forms. The pneumonia treatment coverage will be assessed using baseline, midline and end-line surveys using both qualitative and quantitative data collection methods. ETHICAL AND DISSEMINATION: Ethical approval was obtained from the National Health Research Sciences Committee and the WHO Ethics Committee. The implementation research findings will be disseminated to national-level stakeholders and specifically targeted at District Health Offices, which are responsible for implementing the interventions.

Indexed as

Anti-Bacterial AgentsCase ManagementCommunity Health ServicesPneumoniaChild, PreschoolHumansInfantMalawiResearch DesignAnti-Bacterial AgentsCommunity child healthPaediatric infectious disease & immunisationPAEDIATRICS

Identifiers

PMID41371730
PMCPMC12699558

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.