Evidence map›Paper›PMID 41371658›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Necrotizing Fasciitis Caused by Serotype 7C Streptococcus pneumoniae in Overwhelming Post-splenectomy Infection.

Hidemasa Akazawa, Shinnosuke Fukushima, Kenta Nakamoto, Kohei Oguni, Bin Chang, Yukihiro Akeda, Satoru Sugihara, Miyu Takenaka, Shin Morizane, Hideharu Hagiya

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hidemasa AkazawaDepartment of Infectious Diseases, Okayama University Hospital, Japan.
Shinnosuke FukushimaDepartment of Infectious Diseases, Okayama University Hospital, Japan.
Kenta NakamotoDepartment of Infectious Diseases, Okayama University Hospital, Japan.
Kohei OguniDepartment of Infectious Diseases, Okayama University Hospital, Japan.
Bin ChangDepartment of Bacteriology I, National Institute of Infectious Diseases, Japan.
Yukihiro AkedaDepartment of Bacteriology I, National Institute of Infectious Diseases, Japan.
Satoru SugiharaDepartment of Dermatology, Okayama University Hospital, Japan.
Miyu TakenakaDepartment of Dermatology, Okayama University Hospital, Japan.
Shin MorizaneDepartment of Dermatology, Okayama University Hospital, Japan.
Hideharu HagiyaDepartment of Infectious Diseases, Okayama University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overwhelming post-splenectomy infection is a life-threatening condition typically caused by Streptococcus pneumoniae. Necrotizing fasciitis is a rare manifestation of invasive pneumococcal disease. A 73-year-old woman with a history of living-donor liver transplantation and splenectomy for primary biliary cholangitis presented with bilateral leg swelling, pain and altered consciousness. S. pneumoniae serotype 7C, sequence type 2758, was isolated from the blood and wound cultures. Despite intensive care and surgery, the patient developed liver graft failure and died on day 42. The emergence of non-vaccine serotypes highlights the urgent need for next-generation vaccines that target emerging strains.

Indexed as

Fasciitis, NecrotizingPneumococcal InfectionsSplenectomyStreptococcus pneumoniaeAgedFatal OutcomeFemaleHumansSerogroupinvasive pneumococcal diseasenecrotizing fasciitisoverwhelming post-splenectomy infectionserotype 7CStreptococcus pneumoniae

Identifiers

PMID41371658
PMCPMC13521636

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.