ArticleInternal medicine (Tokyo, Japan)2026
Polychondritis and Arthritis in a Patient with Coexisting Alkaptonuria and Psoriasis Vulgaris.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Alkaptonuria is an organic acid metabolic disorder caused by abnormalities of the tyrosine metabolic pathway. Herein, we report a case of relapsing polychondritis and arthritis in a patient with alkaptonuria and psoriasis vulgaris, respectively. A 53-year-old man, previously diagnosed with alkaptonuria and psoriasis vulgaris, was found to have auricular thickening and tenderness, bilateral bulbar conjunctival injection, and elevated C-reactive protein levels. Ultrasound imaging revealed enthesitis in the bilateral knee joints. A biopsy of the auricular cartilage revealed lymphocytic infiltration. The coexistence of ocular involvement, auricular chondritis, and enthesitis was considered indicative of alkaptonuria complicated by relapsing polychondritis and psoriatic arthritis.
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