Evidence map›Paper›PMID 41371642›Full record

ArticleInternal medicine (Tokyo, Japan)2026

New-onset Anti-melanoma Differentiation-associated Gene 5 Antibody Positive Clinically Amyopathic Dermatomyositis Following COVID-19.

Yu Nakanishi, Hirofumi Watanabe, Mako Tsuyuki, Shinji Kakumoto, Masaaki Abe, Kosuke Hamai

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. How loss-of-function mutations inJournal of translational autoimmunity · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu NakanishiDepartment of Respiratory Internal Medicine, Hiroshima City North Medical Center Asa Citizens Hospital, Japan.
Hirofumi WatanabeDepartment of Clinical Immunology and Rheumatology, Onomichi General Hospital, Japan.
Mako TsuyukiDepartment of Respiratory Internal Medicine, Hiroshima City North Medical Center Asa Citizens Hospital, Japan.
Shinji KakumotoDepartment of Respiratory Internal Medicine, Hiroshima City North Medical Center Asa Citizens Hospital, Japan.
Masaaki AbeDepartment of Respiratory Internal Medicine, Hiroshima City North Medical Center Asa Citizens Hospital, Japan.
Kosuke HamaiDepartment of Respiratory Internal Medicine, Hiroshima City North Medical Center Asa Citizens Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, is a life-threatening respiratory illness that shares clinical similarities with autoimmune diseases, which some patients subsequently develop. We herein report a case of an older Japanese patient who presented with skin rash, relapsing progressive interstitial lung disease, and anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody seropositivity after COVID-19 infection. Although the patient was elderly, her symptoms improved with the administration of corticosteroids, tacrolimus, and intravenous cyclophosphamide, indicating that this combination may be a viable treatment option for anti-MDA5 antibody-positive pneumonia, which is a complication of COVID-19.

Indexed as

AutoantibodiesCOVID-19DermatomyositisInterferon-Induced Helicase, IFIH1AgedCyclophosphamideFemaleHumansImmunosuppressive AgentsSARS-CoV-2TacrolimusAutoantibodiesCyclophosphamideIFIH1 protein, humanImmunosuppressive AgentsInterferon-Induced Helicase, IFIH1Tacrolimusamyopathic dermatomyositisanti-melanoma differentiation-associated gene 5 antibodyautoimmune diseasescoronavirus disease 2019intravenous cyclophosphamide

Identifiers

PMID41371642
PMCPMC13447534

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.