Evidence map›Paper›PMID 41371623›Full record

ArticleNano letters2025

Semisynthetic Ferritin Nanocages for Flexible, Site-Specific Targeting and Ligand-Free Activation of Membrane Receptors.

Andreas Neusch, Christina Siepe, Liesa Zitzke, Alexandra C Fux, Cornelia Monzel

Abstract read
In one paragraph

Article in Nano letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreas NeuschExperimental Medical Physics, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0001-8020-9311
Christina SiepeExperimental Medical Physics, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Liesa ZitzkeExperimental Medical Physics, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Alexandra C FuxDepartment of Biosciences & Medical Biology, Paris Lodron University of Salzburg, 5020 Salzburg, Austria.
Cornelia MonzelExperimental Medical Physics, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-0892-3427

Funding

Centre of Advanced ImagingDFG Collaborative Research CenterNorth Rhine–WestphaliaVolkswagenFoundation
6 · The paper itself

Abstract

Homopolymerization and cluster formation of cellular membrane receptors (MRs) are increasingly recognized as an essential facet of cell signaling and modulator of physiological responses. Yet, there is a lack of tools that can mediate precise stimulation to better understand the mechanisms and effects of clustering. Here, we designed fluorescent semisynthetic nanoparticles (NPs) based on the iron-storage protein ferritin and

Indexed as

FerritinsNanoparticlesReceptors, TransferrinAntigens, CDApoptosisHumansLigandsStaphylococcus aureusAntigens, CDCD71 antigenFerritinsLigandsReceptors, TransferrinCD95ferritinmembrane receptorsnanoparticletargetingTfR1

Identifiers

PMID41371623
PMCPMC12766732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.