Evidence map›Paper›PMID 41370562›Full record

Trial reportJornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia2025

Effect of combined strength and endurance training in adults with asthma: a randomized controlled trial.

Giuseppe Lo Bello, Federico Mattia Oliva, Alberto Malovini, Nicolino Ambrosino, Matteo Tarasconi, Andrea Zanini, Elisabetta Zampogna

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe Lo Bello. Division of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.ORCID http://orcid.org/0009-0001-3978-8347
Federico Mattia Oliva. Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID http://orcid.org/0000-0002-6089-8524
Alberto Malovini. Laboratory of Medical Informatics and Artificial Intelligence, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.ORCID http://orcid.org/0000-0003-2857-5773
Nicolino Ambrosino. Istituti Clinici Scientifici Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Montescano, Montescano, Pavia, Italy.ORCID http://orcid.org/0000-0002-5331-1393
Matteo Tarasconi. Division of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.ORCID http://orcid.org/0000-0003-1829-306X
Andrea Zanini. Pulmonary Rehabilitation, Cliniche di Riabilitazione Ente Ospedaliero Cantonale (CREOC), Novaggio, Switzerland.ORCID http://orcid.org/0009-0002-2750-6231
Elisabetta Zampogna. Division of Pulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.ORCID http://orcid.org/0000-0003-0927-1694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePulmonary rehabilitation programs, including exercise training, have an established role in the treatment of chronic respiratory diseases but are not routinely used in asthma. Most studies of individuals with asthma have focused on endurance training, and there is therefore limited data available on strength training. The aim of this study was to evaluate the effects that adding strength training to a program of endurance training and education has on the quality of life of such individuals.

methodsIn this single-center, parallel-group randomized controlled trial, adults with moderate-to-severe asthma admitted for in-hospital pulmonary rehabilitation between June of 2021 and October of 2022 were randomized to either a study group (SG) or a control group (CG). The SG received strength training alongside endurance training and education, whereas the CG received the same endurance training and education, along with sham mobility exercise training instead of strength training. The primary outcome was the change in the Asthma Quality of Life Questionnaire (AQLQ) score from hospital admission to discharge.

resultsA total of 61 participants were randomized, with 31 being assigned to the SG and 30 being assigned to the CG. At discharge, the AQLQ score showed significant improvement in both groups (p < 0.001 for the SG and p = 0.02 for the CG), albeit without a significant difference between the groups (p > 0.99). In contrast, peripheral muscle strength improved significantly from admission to discharge only in the SG, with a significant difference between the groups in terms of quadriceps strength (p = 0.03).

conclusionsAdding strength training to endurance training and education does not seem to result in further improvement in the quality of life of individuals with moderate-to-severe asthma.

Indexed as

AsthmaEndurance TrainingResistance TrainingAdultFemaleHumansMaleMiddle AgedMuscle StrengthQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID41370562
PMCPMC13143777

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.