Observational studyJBRA assisted reproduction2025
Characterization of infertile couples and outcomes of their first in vitro fertilization cycle at public fertility centers in Northern and Central Portugal: a five-year cohort study.
Observational study in JBRA assisted reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- Gender perception as a predictor of women's attitudes towards infertility: a cross-sectional study.BMC women's health · 2026Article
- Living with adenomyosis and involuntary childlessness: a qualitative interview study.BMC women's health · 2026Article
- Identifying Key Determinants of Fertility Among Women in Bangladesh Using Machine Learning Tools: Evidence From the BDHS 2022.Health science reports · 2026Article
- Development and Internal Evaluation of an Integrated Patient-Embryo-Endometrial Scoring System for Predicting Biochemical Pregnancy in IVF: A Proof-of-Concept Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Live Births Following IVF-FET in Two Adult Sisters with Nonclassic P450 Oxidoreductase Deficiency: A Case Report Identifying a Novel POR Variant.International journal of women's health · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInfertility is a major global health issue, with assisted reproductive technologies (ART) commonly employed as a solution. Although numerous factors related to couple characteristics and ART cycles are implicated in pregnancy outcomes, data on infertile couples in Portugal are limited. The Portuguese Northern and Central Regions Infertility Study 2014-2018 (NORCE-INF 14-18) aimed to evaluate how couple characteristics and in vitro fertilization (IVF) cycle parameters affect the success of the first IVF treatment, specifically through cumulative live birth rate (CLBR).
methodsThis multicenter, observational, longitudinal, retrospective cohort study gathered data from six public fertility centers in Northern and Central Portugal, involving couples undergoing their first IVF treatment from January 2014 to December 2018, along with subsequent frozen embryo transfers (FET).
resultsThe analysis included 5,250 couples, with mean female and male ages of 34.3 and 36.1 years, respectively. The average duration of infertility was 45.88 months, predominantly resulting from male factor infertility. Among 3,767 cycles with fresh embryo transfers, the live birth rate was 29.5%. Additionally, the study found a CLBR of 25.5%, leading to 1,601 live births. Logistic regression identified female age as a key predictor of ART success, showing an inverse relationship with pregnancy rates.
conclusionsThe NORCE-INF 14-18 study represents the largest analysis of ART outcomes in Portugal, revealing that approximately 26% of couples achieved live births after their first IVF cycle, emphasizing the importance of demographic factors in treatment success.
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