Evidence map›Paper›PMID 41370287›Full record

ArticleChemistry & biodiversity2026

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola.

Josefa Rangel, Ângela Liberal, Tiane C Finimundy, Tânia S P Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M Romeiras, Ângela Fernandes

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Josefa RangelLinking Landscape, Environment, Agriculture and Food Research Center (LEAF), Associated Laboratory TERRA, Instituto Superior de Agronomia (ISA), Universidade de Lisboa, Lisboa, Portugal.
Ângela LiberalCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal.
Tiane C FinimundyCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal.
Tânia S P PiresCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal.
Pedro CravoGlobal Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, (LA-REAL), Instituto de Higiene e Medicina Tropical, (IHMT), Universidade NOVA De Lisboa (UNL), Lisboa, Portugal.ORCID https://orcid.org/0000-0003-1675-4504
Maria Conceição SilvaGlobal Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, (LA-REAL), Instituto de Higiene e Medicina Tropical, (IHMT), Universidade NOVA De Lisboa (UNL), Lisboa, Portugal.
Gustavo Capatti CassianoGlobal Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, (LA-REAL), Instituto de Higiene e Medicina Tropical, (IHMT), Universidade NOVA De Lisboa (UNL), Lisboa, Portugal.
Lillian BarrosCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal.ORCID https://orcid.org/0000-0002-9050-5189
Maria M RomeirasLinking Landscape, Environment, Agriculture and Food Research Center (LEAF), Associated Laboratory TERRA, Instituto Superior de Agronomia (ISA), Universidade de Lisboa, Lisboa, Portugal.ORCID https://orcid.org/0000-0002-9373-6302
Ângela FernandesCIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal.ORCID https://orcid.org/0000-0002-0157-9873

Funding

COMPUTER AIDED ANALYSIS OF ELECTROCARDIOGRAPHYZ01CT000002 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI BAILEY, JAMES J. · 1985 to 2003
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Intramural NIH HHS Z01 CT000002
6 · The paper itself

Abstract

Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating their antioxidant, antimalarial, and antimicrobial potential. Our results showed a vibrant phenolic profile in all the studied species, with A. muricata standing out with 44 compounds identified, with leaves containing the highest concentration of total phenolic compounds, particularly in A. senegalensis. Procyanidin trimer was the primary compound found in A. muricata leaf and stem bark hydroethanolic extract and infusion preparation, while in A. squamosa, epigallocatechin and catechin prevail. In A. senegalensis, quercetin-3-O-rutinoside was primarily detected in the leaves and isorhamnetin-3-O-rutinoside in the stem barks. Extracts from A. senegalensis performed a higher antioxidant capacity, while the hydroethanolic extract of A. muricata displayed better antimalarial activity. A. senegalensis showed the highest antioxidant activity, while A. muricata extract was most effective against malaria; all extracts displayed antibacterial effects. These results reveal the remarkable phenolic richness and bioactive potential of the studied species, supporting their traditional medicinal uses and emphasizing the pharmaceutical and industrial relevance of Annona species.

Indexed as

AnnonaAnti-Bacterial AgentsAntimalarialsAntioxidantsPhenolsPlant ExtractsAngolaBiphenyl CompoundsMicrobial Sensitivity TestsParasitic Sensitivity TestsPicratesPlant BarkPlant LeavesPlasmodium falciparum1,1-diphenyl-2-picrylhydrazylAnti-Bacterial AgentsAntimalarialsAntioxidantsBiphenyl CompoundsPhenolsPicratesPlant ExtractsAfrican useful floraAnnonaceaeantimalarialantimicrobialantioxidantphenolic compounds

Identifiers

PMID41370287
PMCPMC12860525

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.