Evidence map›Paper›PMID 41369982›Full record

ReviewAddiction biology2025

A Review of Exercise Interventions for Rehabilitation in Drug-Dependent Individuals.

Qinghua He, Li Zhu, Zhaosong Wang, Hao Wang, Yiyi Jiang, Xin Wang, Fuxuan Luo, Chaoyi Zhu, Changlong Zhan

Abstract readReview
In one paragraph

Review in Addiction biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qinghua HeGuangxi Minzu University, Nanning, China.
Li ZhuGuangxi Minzu University, Nanning, China.
Zhaosong WangGuangxi Minzu University, Nanning, China.ORCID 0009-0009-5571-969X
Hao WangGuangxi Minzu University, Nanning, China.
Yiyi JiangGuangxi College of Sports Education, Nanning, China.
Xin WangThe Sixth Compulsory Isolation and Rehabilitation Center of Guangxi, Nanning, China.
Fuxuan LuoThe Sixth Compulsory Isolation and Rehabilitation Center of Guangxi, Nanning, China.
Chaoyi ZhuThe Sixth Compulsory Isolation and Rehabilitation Center of Guangxi, Nanning, China.
Changlong ZhanThe Sixth Compulsory Isolation and Rehabilitation Center of Guangxi, Nanning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study systematically investigates the multidimensional rehabilitative effects and neurobiological mechanisms of exercise interventions in individuals with substance use disorders (SUDs). By synthesizing and critically analysing current evidence, the aim is to establish a theoretical framework for exercise-based rehabilitation and provide empirical support for optimizing intervention strategies. A comprehensive literature review was conducted, encompassing 39 core studies on exercise interventions in drug rehabilitation. Evidence-based medicine principles were applied to integrate mechanistic findings and evaluate effect sizes. The review focused on examining the physiological, psychological and neurobiological effects of various exercise modalities in individuals with SUD. Findings consistently demonstrate that exercise interventions are effective in reducing drug craving and withdrawal symptoms, improving overall quality of life and potentially lowering relapse rates. For individuals undergoing rehabilitation, exercise promotes improvements in physical health, psychological well-being and social functioning, while concurrently attenuating relapse vulnerability. As a nonpharmacological, multitarget intervention, exercise therapy exhibits significant potential in promoting neuroplasticity and facilitating psychological recovery in individuals with SUD. Standardized exercise prescriptions should be integrated into existing rehabilitation frameworks. Future research should emphasize comparative effectiveness across exercise modalities, explore the benefits of multimodal interventions, and further elucidate the interplay between biological, clinical and psychosocial mechanisms to enhance long-term rehabilitation outcomes.

Indexed as

Exercise TherapySubstance-Related DisordersCravingHumansQuality of LifeSubstance Withdrawal Syndromebenefit mechanismsdrug addictionexercise‐based drug rehabilitationexercise intervention

Identifiers

PMID41369982
PMCPMC12692742

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.