Evidence map›Paper›PMID 41369831›Full record

ArticleGeroScience2026

Age-related change in skeletal muscle strength, size, and adiposity over 18 years in Caribbean men.

Lauren S Roe, Ryan K Cvejkus, Victor W Wheeler, Christopher L Gordon, Tanya S Kenkre, Joseph M Zmuda, Iva Miljkovic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren S RoeDivision of Geriatric Medicine, Department of Medicine, University of Pittsburgh School of Medicine, 130 N Bellefield Ave, Suite 300, Pittsburgh, PA, 15213, USA. las367@pitt.edu.ORCID http://orcid.org/0000-0003-3557-5042
Ryan K CvejkusDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Victor W WheelerTobago Health Studies Office, Scarborough, Tobago, Trinidad and Tobago.
Christopher L GordonDepartment of Radiology, McMaster University, Hamilton, ON, Canada.
Tanya S KenkreDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Joseph M Zmuda *Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.
Iva Miljkovic *Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Epidemiology of Bone Loss in African MenR01AR049747 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZMUDA, JOSEPH M. · 2003 to 2014
$5.9M
Myosteatosis, Cognition, and Blood Biomarkers of Alzheimer's Disease in Persons of African AncestryRF1AG077474 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA, ROSANO, CATERINA · 2022 to 2024
$3.6M
The Study of Muscle and Physical Performance in African Caribbeans.R01AG074956 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI IVA MILJKOVIC · 2022 to 2026
$2.5M
Ectopic adiposity in black men with high type 2 diabetes riskR01DK097084 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2013 to 2016
$1.9M
NIAMS NIH HHS R01 AR049747NIAMS NIH HHS R01-AR049747NIA NIH HHS R01 AG074956NIA NIH HHS R01-AG074956NIA NIH HHS RF1 AG077474NIA NIH HHS RF1AG077474NIA NIH HHS T32 AG021885NIA NIH HHS T32-AG021885NIDDK NIH HHS R01 DK097084NIDDK NIH HHS R01-DK097084
6 · The paper itself

Abstract

Declines in muscle strength outpace declines in muscle mass with age, so factors like muscle adiposity (i.e., myosteatosis) may contribute to strength loss. We describe intermuscular adipose tissue (IMAT) and grip strength over 18 years among middle-aged and older African Caribbean men. We hypothesized that increases in IMAT precede the loss of muscle area and strength, and that increased IMAT is independently associated with strength decline. Men (n = 339, 51.2 ± 5.5 years) were followed for 18.2 ± 0.9 years. Peripheral quantitative computed tomography at the calf determined IMAT (cm

Indexed as

AdiposityAgingMuscle, SkeletalMuscle StrengthAdipose TissueAgedHand StrengthHumansMaleMiddle AgedTomography, X-Ray ComputedEpidemiologyGrip strengthIntermuscular adipose tissueMyosteatosisPQCT

Identifiers

PMID41369831
PMCPMC13601445

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.