Evidence map›Paper›PMID 41369812›Full record

SynthesisAnnals of surgical oncology2026

Evaluating Surgical Approaches in Early NSCLC: A Meta-Analysis of Robot-Assisted and Video-Assisted Techniques.

Wania Khan, Talha Ali, Mustafa Bilal, Waqas Ahmad, Sana Aijaz Ali, Ali Hashim, Amna Zaman Khan, Anish Kumar, Muhammad Abdullah, Sameen Khan and 2 more

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. RoboticJournal of thoracic disease · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wania KhanDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Talha AliShaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan. talhaali190@gmail.com.ORCID http://orcid.org/0009-0000-3208-653X
Mustafa BilalPeshawar Medical College, Peshawar, Pakistan.
Waqas AhmadKing Edward Medical University, Lahore, Pakistan.
Sana Aijaz AliBahria Medical College, Karachi, Pakistan.
Ali HashimAl-Aleem Medical College, Lahore, Pakistan.
Amna Zaman KhanAl-Aleem Medical College, Lahore, Pakistan.
Anish KumarZiauddin Medical College, Ziauddin University, Karachi, Pakistan.
Muhammad AbdullahDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Sameen KhanNishtar Medical College, Multan, Pakistan.
Ashhal AhmedZiauddin Medical College, Ziauddin University, Karachi, Pakistan.
Mohammad JawadDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer, especially non-small cell lung cancer (NSCLC), is a leading cause of cancer death. Surgical resection is the primary treatment for early-stage NSCLC. Video-assisted thoracoscopic surgery (VATS) and robot-assisted thoracic surgery (RATS) are minimally invasive options, with RATS offering better precision at higher costs. This meta-analysis compared the perioperative outcomes of both techniques in NSCLC.

methodsA systematic search in PubMed, Web of Science, NLM, CNKI, and Wanfang was conducted for RCTs published between 31 July 2021 and 31 December 2024. Primary outcomes included operation time, blood loss, lymph node dissection, conversion to thoracotomy, chest drainage time, and hospital stay. Statistical analyses were performed using RevMan 5.3, with heterogeneity assessed using the I

resultsThree RCTs were analyzed. Blood loss showed no significant difference between VATs and RATs (mean difference [MD], -33.00; 95% CI, -85.51 to 22.89; p = 0.07). Conversion to thoracotomy was comparable (MD, 0.69; 95% CI, 0.37 to 1.28; p = 0.24). Hospital stay did not differ significantly (MD, 0.13; 95% CI, -0.58 to 0.84; p = 0.74). Operation time remained similar (MD, -4.63; 95% CI, -10.93 to 1.67; p = 0.15). The VATS procedure enabled significantly greater lymph node dissection (MD, 1.83; 95% CI, 0.16 to 3.49; p = 0.03). Chest drainage duration showed no difference (MD, 0.00; 95% CI, -0.27 to 0.27; p = 1.00).

conclusionIn NSCLC, RATS and VATS yield comparable outcomes, with RATS potentially reducing blood loss and VATS allowing more lymph node dissection. Further high-quality RCTs are needed to clarify the optimal approach for NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsPneumonectomyRobotic Surgical ProceduresThoracic Surgery, Video-AssistedHumansLength of StayLymph Node ExcisionOperative Time

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.