ArticleMolecular biology reports2025
Molecular basis of delayed BSMYV infection in diploid Musa balbisiana, a banana progenitor.
Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundBanana streak MY virus (BSMYV) [Badnavirus gammavirgamusae] is one of the most prevalent badnaviruses associated with streak disease in Musa species. Its infection and symptom development vary across the banana genotypes. Present study, for the first time attempted successful agroinfection of BSMYV in diploid banana progenitor Musa balbisiana cv. Bhimkol (BB) which was earlier considered resistant and elucidated the underlying mechanism of infection. METHODS AND
resultsAgroinfection of Bhimkol banana showed delayed infection at 280 days post-BSMYV agroinoculation. High-throughput sequencing (HTS) was carried out to decipher the mechanisms of delayed BSMYV infection. De novo assembly of transcriptome generated 101,961 unigenes with a mean length of 1310 base pairs (bp). Out of the total coding sequence (CDS), 48,797 were annotated against the non-redundant protein database. A total of 3174 differentially expressed genes (DEGs) were identified, of which 1138 up-regulated and 2036 down-regulated genes were observed in comparison of mock inoculated (BB_Mock) and delayed infected (BB_Symptomatic) Bhimkol banana. A heatmap with hierarchical clustering of top 50 significantly differentially expressed genes showed four different clusters. Based on fold changes, and adjusted p-value, twelve selected DEGs were validated using quantitative-PCR (qPCR). Selected DEGs were associated with regulation of plant hormone, host defense system and host machinery hijack. Enrichment analysis of differentially expressed genes hints toward the importance of Ca2+ dependent Ras signaling in M. balbisiana (BB) exhibiting delayed BSMYV infection response.
conclusionThe present study revealed a complex cross-talk between Ca2+ dependent Ras, macromolecules localization and auxin responsive genes to regulate primary metabolite production that possibly hinder the spread of virus across the cell, leading to the delayed establishment of BSMYV infection in Bhimkol banana. To the best of our knowledge, this is first report on elucidation of delayed infection of BSMYV in diploid M. balbisiana (BB) through comprehensive transcriptome analysis.
Indexed as
Identifiers
41369801What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.