Evidence map›Paper›PMID 41369595›Full record

ReviewJournal of bacteriology2026

Functional insights into the photoactive yellow protein family from homologs, multidomain proteins, and inferred

Rosalie L Dohmen, Gunnar Hoogerwerf, Amber J Dohmen, Madison L Neal, Catalina Bradley, Clarice Huffman, Sarah M Teeman, Saylor F Hampton, Scout Powell, Zariah Gunn and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rosalie L DohmenDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.ORCID 0009-0009-4314-5561
Gunnar HoogerwerfDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Amber J DohmenDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Madison L NealDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Catalina BradleyDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Clarice HuffmanDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Sarah M TeemanDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Saylor F HamptonDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Scout PowellDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Zariah GunnDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Wouter D HoffDepartment of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.ORCID 0009-0004-7523-6576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoactive Yellow Protein (PYP) is a model system for functional protein dynamics and a prototype of the PAS domain superfamily. It is a bacterial photoreceptor that triggers a range of responses in different bacteria: phototaxis, biosynthesis of photo-protective pigments, and light regulation of biofilm formation. An important gap in knowledge on PYP is the signal transduction chain that guides the initial signal from the photoreceptor to various biological responses. Here, we present an expanded set of 984 PYP homologs, providing information on sequence conservation and variation. We analyze this set of PYPs using two bioinformatics approaches to identify candidate proteins that are functionally related to PYP. First, we identified 153 multi-domain proteins containing PYP and analyzed the domain composition of these proteins. Specific preferences for N- or C-terminal placement of the PYP domain were observed. Second, we identified 113 predicted multi-gene operons containing the

Indexed as

Bacterial ProteinsOperonPhotoreceptors, MicrobialComputational BiologyGene Expression Regulation, BacterialMultigene FamilyProtein DomainsSignal TransductionBacterial Proteinsphotoactive yellow protein, BacteriaPhotoreceptors, Microbialbiofilmdomain structureoperon structurephotobiologyphotoreceptorsphototaxissignal transduction

Identifiers

PMID41369595
PMCPMC12826048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.