ArticleAntimicrobial agents and chemotherapy2026
The heme A synthase Cox15, as a target of redox-active 3-benzylmenadiones with antiparasitic activity.
Marcelo L Merli, Claudia Serot, Cindy Vallières, Julia A Cricco, Bogdan I Iorga, Elisabeth Davioud-Charvet, Brigitte Meunier
Abstract read
In one paragraphArticle in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Marcelo L MerliInstituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad Nacional de Rosario (UNR), Rosario, Santa Fe, Argentina.
Claudia SerotUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Cindy VallièresUniversité Paris-Saclay, CNRS UPR 2301, Institut de Chimie des Substances Naturelles (ICSN), Gif-sur-Yvette, France.
Julia A CriccoInstituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Universidad Nacional de Rosario (UNR), Rosario, Santa Fe, Argentina.
Bogdan I IorgaUniversité Paris-Saclay, CNRS UPR 2301, Institut de Chimie des Substances Naturelles (ICSN), Gif-sur-Yvette, France.ORCID 0000-0003-0392-1350 Elisabeth Davioud-CharvetUMR7042 CNRS-Unistra-UHA, Laboratoire d'Innovation Moléculaire et Applications (LIMA), European School of Chemistry, Polymers and Materials (ECPM), Strasbourg, France.ORCID 0000-0001-7026-4034 Brigitte MeunierUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.ORCID 0000-0002-6988-4663 Funding
Agence Nationale de la Recherche ANR-11-LABX-0024Agence Nationale de la Recherche ANR-22-CE93-0005-01Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT I A 2021-00274
6 · The paper itselfAbstract
Chagas disease, caused by
Indexed as
Antiparasitic AgentsSaccharomyces cerevisiae ProteinsTrypanocidal AgentsTrypanosoma cruziChagas DiseaseElectron Transport Complex IVHemeOxidation-ReductionSaccharomyces cerevisiaeAntiparasitic AgentsElectron Transport Complex IVHemeheme aSaccharomyces cerevisiae ProteinsTrypanocidal Agentsantiparasitic drugdrug mode of actionmitochondrial respiratory chainyeast model
Identifiers
PMID41369564
PMCPMC12777560
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