ArticlePrenatal diagnosis2026
Can Prenatal Ultrasonographic Markers Predict Enteral Feeding Tolerance in Neonates With Fetal Omphalocele?
Article in Prenatal diagnosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Can Prenatal Ultrasonographic Markers Predict Enteral Feeding Tolerance in Neonates With Fetal Omphalocele?Prenatal diagnosis · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to identify prenatal ultrasonographic predictors of enteral feeding tolerance in neonates with omphaloceles.
methodThis retrospective cohort study included all live-born neonates prenatally diagnosed with omphalocele at Emma Children's Hospital/Amsterdam UMC approximately 2004-2024. Prenatal ultrasonographic data included fetal ascites, omphalocele circumference/abdominal circumference (OC/AC) ratio, extracorporeal liver, polyhydramnios and associated structural anomalies. Associations with enteral feeding tolerance, measured by duration of parenteral nutrition (PN) and time to achieve full enteral feeds (FEF), and the need for tube feeding post-admission were analyzed using linear and logistic regression.
resultsForty-two neonates were included (42.9% male). Median time to FEF was 10.0 days (IQR = 5.8-14.5) and median PN duration 5.0 days (IQR = 0.0-10.5). At discharge, 28.6% required full or partial nasogastric tube feeding. Polyhydramnios was excluded due to low prevalence (n = 1). Fetal ascites predicted longer PN duration (ratio 4.05, 95% CI [1.57, 10.60]) and tube feeding post-admission (OR 9.27, 95% CI [1.47, 58.40]). A higher OC/AC ratio predicted a longer time to FEF (ratio 4.39, 95% CI [1.54, 12.69]). No associations were found for extracorporeal liver or associated structural anomalies.
conclusionFetal ascites and a higher OC/AC ratio were predictive of delayed enteral feeding tolerance. While full enteral feeds were achieved within 2 weeks, 29% required tube feeding after discharge.
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