ReviewNanomaterials (Basel, Switzerland)2025
The Ubiquitous Use of Polyethylene Glycol in Pharmaceutical Design and Development: Technological Aspects and Future Perspectives.
Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Curcumin-loaded PEGylated Magnetic Iron Oxide Nanoparticles: a Biogenic Platform for Targeted and Controlled Drug Release.Applied biochemistry and biotechnology · 2026Article
- Phytochemical Profiling, Biological Activities, and Development of Hydrogel Sheets ContainingGels (Basel, Switzerland) · 2026Article
- Nanosomes in Precision Nanomedicine (Second Edition).Nanomaterials (Basel, Switzerland) · 2026Article
- Protein-Based Nanomaterials for Cancer Therapy: A Comparative and Translational Perspective.Pharmaceutics · 2026Review
- Effect of the Nature of Metal Ions and the Type of Solvent on the Mechanical, Self-Healing and Conductive Properties of Poly(AA-Co-AAm) Gels.Gels (Basel, Switzerland) · 2026Article
- Development and Study of Hydrophilic Ointment Compositions with a Dextrin/Polyvinyl Alcohol/Iodine Complex (D/PVA/I).Pharmaceuticals (Basel, Switzerland) · 2026Article
- Empirical Structure-Property Relationships of PLLA-Polymers · 2026Article
- Potential of Silver Nanoparticles in Imaging Diagnostics and Image-Guided Applications: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Special Issue "Polymeric Materials for Biomedical Applications, Drug and Gene Delivery".International journal of molecular sciences · 2026Article
- Harnessing Endophytic Fungi as a Sustainable Source of Novel Anticancer Agents: Opportunities, Challenges, and Future Directions.Molecules (Basel, Switzerland) · 2026Review
- Functionalization of carbon nanospheres with curcumin, polyethylene glycol and folic acid: potential use as drug carriers.RSC advances · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyethylene glycol (PEG) has been extensively utilized in drug formulations due to its multifunctional properties, i.e., hydrophilicity and biocompatibility. The roles played by PEG (as a drug delivery carrier and a solubilizer) improve the dissolution profile of several active pharmaceutical ingredients (APIs), leading to an improved absorption, distribution, metabolism, excretion, and toxicity (ADMET) profile. Moreover, PEG aids in upgrading the existing mechanical properties (as a binding agent, a plasticizer, etc.). Furthermore, PEG, due to its unique ability to provide "stealth" properties, is a valuable tool in pharmaceutical nanotechnology. Exploiting physicochemical variables, PEG acts as a coating/conjugation component of nanocarriers for ameliorating permeability and enhancing in vivo circulation without clearance by the body's immune system. Additionally, PEG's presence at the target site decreases external interactions and enhances the pharmacological attributes in terms of loading efficiency and controlled release. Nevertheless, cases of hypersensitivity or allergy, as well as anaphylactic shocks and allergic reactions, have been detected. The topic of this article is the exploitation of PEG's physicochemical properties in the study of drug delivery, focusing on solid dosage forms and nanovesicles, along with the evaluation of its contribution to the fabrication of safe delivery and theragnostic systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.