Evidence map›Paper›PMID 41369327›Full record

ReviewCells2025

Advancements in Cellular Therapeutics in Corneal Diseases.

Elizabeth Woo, Daniel Henick, Maryam Tahvildari

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth WooInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT 06511, USA.ORCID 0000-0002-7060-7575
Daniel HenickDepartment of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT 06511, USA.ORCID 0000-0002-1836-8626
Maryam TahvildariDepartment of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT 06511, USA.ORCID 0000-0003-1541-118X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disorders of the cornea are responsible for a significant portion of preventable blindness worldwide. Various types of corneal transplantation procedures have successfully restored vision in many individuals; however, they carry the risk of graft failure due to immune rejection, endothelial cell dysfunction, infections and limbal stem cell deficiency. Thus, regenerative therapies of the cornea serve as promising alternatives or adjunct therapies. With improved understanding of limbal stem cell function and advancement in limbal stem cell culture technologies, major progress has been made in the in vivo and ex vivo cell-based therapies for treatment of corneal diseases. In this review, we summarize the recent developments achieved in cell-based therapeutics to target corneal epithelial, stromal, and endothelial cell disorders.

Indexed as

Cell- and Tissue-Based TherapyCorneal DiseasesAnimalsHumansStem CellsStem Cell Transplantationcorneal blindnesscorneal endothelial cellscorneal epithelial stem cellscorneal stromal cellsmesenchymal stem cellsregenerative medicine

Identifiers

PMID41369327
PMCPMC12691177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.