SynthesisClinical and experimental dental research2025
Clinical Outcomes of Titanium Mesh for Alveolar Bone Augmentation: An Umbrella Review.
Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of engineered scaffolds for horizontal and vertical ridge augmentation: A systematic review and meta-analysis.Journal of periodontology · 2026Pooled it
- Clinical Outcomes of Titanium Mesh for Alveolar Bone Augmentation: An Umbrella Review.Clinical and experimental dental research · 2025Pooled it
- Clinical application of digital technology in bone augmentation: a narrative review.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectivesTo critically evaluate the evidence derived from systematic reviews for titanium mesh as a bone augmentation method for alveolar ridge deficiencies. MATERIALS AND
methodsFive databases were searched for systematic reviews describing any interventions to increase the dimensions of the alveolar ridge using titanium mesh. Included reviews had to report on the primary outcome of vertical and/or horizontal bone gain after augmentation with titanium mesh. The methodological quality of the systematic reviews was assessed with the AMSTAR 2 tool, and the certainty of evidence was evaluated with GRADE.
resultsEight systematic reviews were identified, including two with meta-analysis. Of the 51 index studies included in the reviews, 20 were RCTs. The weighted mean reported vertical bone gain was 4.05 mm, and horizontal gain was 3.96 mm. However, overlap of primary studies across included reviews limits the precision of these estimates. When stratified by review quality, the single high-quality review showed lower vertical and horizontal bone gain compared to the weighted mean. The average mesh exposure rate was 25%, although bone regeneration was usually still sufficient for implant placement.
conclusionsTitanium mesh can be effective for bone regeneration but carries a notable risk of site exposure. When choosing the technique for bone augmentation, clinicians should balance achieving optimal bone regeneration with minimal complications to enhance patient care and surgical outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.