Evidence map›Paper›PMID 41368851›Full record

ArticleRenal failure2025

Assessing renal recovery after acute kidney injury in elderly patients: a retrospective cohort study.

Qinglin Li, Xiaonan Ding, Hanyu Zhu, Guangyan Cai, Xiangmei Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qinglin LiSenior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine (zyyzdxk-2023310), Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine. (No: ZYYCXTD-D-202402), Beijing, China.
Xiaonan DingSenior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine (zyyzdxk-2023310), Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine. (No: ZYYCXTD-D-202402), Beijing, China.
Hanyu ZhuSenior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine (zyyzdxk-2023310), Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine. (No: ZYYCXTD-D-202402), Beijing, China.
Guangyan CaiSenior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine (zyyzdxk-2023310), Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine. (No: ZYYCXTD-D-202402), Beijing, China.
Xiangmei ChenSenior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Medical Devices and Integrated Traditional Chinese and Western Drug Development for Severe Kidney Diseases, Beijing Key Laboratory of Digital Intelligent TCM for the Prevention and Treatment of Pan-vascular Diseases, Key Disciplines of National Administration of Traditional Chinese Medicine (zyyzdxk-2023310), Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine. (No: ZYYCXTD-D-202402), Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to examine different acute kidney injury (AKI) recovery patterns in elderly patients and assess their association with long-term outcomes after AKI. This retrospective study included elderly patients admitted to the Chinese PLA General Hospital between 2007 and 2022. Early recovery was defined as renal function recovery documented a week after AKI diagnosis. Recovery of AKI was defined as being alive for over 7 days and when the patient's serum creatinine level returned to below 1.2 times, the baseline value for at least 2 days post-AKI. A total of 1395 elderly patients were enrolled for eventual analysis; their median age was 88 years. Using the Kidney Disease Improving Global Outcomes stage, 51.7%, 25.9%, 22.4% were in stages 1, 2, and 3, respectively. Four patterns are observed. The most common (423; 30.3%) patients showed late recovery after day 7. The remaining patients (337; 24.2%) had never fully recovered; early recovery was sustained (230; 16.5%) during follow-up, but almost as many patients with early recovery had one or more recurrences (255; 18.3%). Patients with different phenotypes had distinct outcomes, and the 1-year survival rates were 79% for early sustained recovery, 64% for recurrent AKI, and less than 41% for patients who had never recovered. Relative to early sustained recovery, late recovery was related to a 2-fold increase in the 1-year mortality. Four different recovery phenotypes were detected based on the clinical course seven days after AKI diagnosis. These phenotypes contribute to the identification of patients suitable for treatment.

Indexed as

Acute Kidney InjuryKidneyRecovery of FunctionAgedAged, 80 and overChinaCreatinineFemaleGlomerular Filtration RateHumansMaleRecurrenceRetrospective StudiesSurvival RateTime FactorsCreatinineAcute kidney injuryoutcomesrenal functionrisk factors

Identifiers

PMID41368851
PMCPMC12697270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.