Evidence map›Paper›PMID 41368820›Full record

ArticleJournal of the American Heart Association2025

Unplanned Hospitalization Due to All-Cause Morbidity and Its Real-World Management Practices in Patients With Fontan Circulation.

Hideo Ohuchi, Kohta Takei, Jun Muneuchi, Shingo Kasahara, Yuichi Ishikawa, Shota Muraji, Masanori Tsukada, Masaki Nii, Shin Ono, Motoki Takamuro and 13 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Hideo OhuchiDepartment of Pediatric Cardiology and Adult Congenital Heart Disease Center National Cerebral and Cardiovascular Center Suita Japan.ORCID 0000-0001-7092-4792
Kohta TakeiDepartment of Pediatric Cardiology Nagano Children's Hospital Azumino Japan.ORCID 0000-0001-9845-5828
Jun MuneuchiDepartment of Pediatrics, Kyushu Hospital Japan Community Healthcare Organization Fukuoka Japan.
Shingo KasaharaDepartment of Cardiovascular Surgery Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences and Okayama University Hospital Okayama Japan.ORCID 0000-0002-3698-4836
Yuichi IshikawaDepartment of Pediatric Cardiology Fukuoka Children's Hospital Fukuoka Japan.ORCID 0000-0001-8139-685X
Shota MurajiDepartment of Pediatric Cardiology Fukuoka Children's Hospital Fukuoka Japan.ORCID 0000-0001-5654-0864
Masanori TsukadaDepartment of Pediatrics Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.ORCID 0000-0002-0644-3174
Masaki NiiDepartment of Pediatric Cardiology Shizuoka Children's Hospital Shizuoka Japan.ORCID 0000-0002-7498-7181
Shin OnoDepartment of Pediatric Cardiology Kanagawa Children's Medical Center Yokohama Japan.ORCID 0000-0003-3178-0815
Motoki TakamuroDepartment of Pediatric Cardiology Hokkaido Medical Center for Child Health and Rehabilitation Sapporo Japan.ORCID 0000-0002-7662-2602
Hirofumi SaikiDepartment of Pediatrics Iwate Medical University Morioka Japan.
Mitsuhiro FujinoDepartment of Pediatric Cardiology Osaka City General Hospital Osaka Japan.
Kenji KuraishiDepartment of Pediatric Cardiology and Neonatology Ogaki Municipal Hospital Ogaki Japan.ORCID 0000-0002-8651-260X
Lisheng LinDepartment of Pediatrics Ibaraki Children's Hospital Mito Japan.ORCID 0000-0003-4886-4767
Aya MiyazakiDepartment of Transitional Medicine, Division of Congenital Heart Disease Shizuoka General Hospital Shizuoka Japan.ORCID 0000-0003-3401-9378
Ichiro SakamotoDepartment of Cardiovascular Medicine Kyushu University Graduate School of Medical Sciences Fukuoka Japan.ORCID 0000-0002-9494-7275
Satoshi MasutaniDepartment of Pediatrics, Saitama Medical Center Saitama Medical University Kawagoe Japan.ORCID 0000-0002-1551-9089
Yasunobu HayabuchiDepartment of Pediatrics, School of Medicine University of Tokushima Tokushima Japan.ORCID 0000-0001-6143-2673
Hiroyuki OhashiDepartment of Pediatrics Mie University School of Medicine Tsu Japan.ORCID 0000-0001-6542-7222
Kenji YasudaDepartment of Pediatrics Shimane University Faculty of Medicine Izumo Japan.ORCID 0000-0001-8379-769X
Mitsuru SekiDepartment of Pediatrics Jichi Medical University.
Aki MoriDepartment of Pediatric Cardiology and Adult Congenital Heart Disease Center National Cerebral and Cardiovascular Center Suita Japan.
Michikazu NakaiClinical Research Support Center University of Miyazaki Hospital Miyazaki Japan.ORCID 0000-0003-2240-1510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement strategies of unplanned hospitalizations (UPH) vary and have not been well characterized in patients with Fontan circulation.

methodsWe prospectively followed 3226 Fontan patients for 3 years to characterize the current UPH status and elucidate the associations between in-hospital management strategies and postdischarge outcomes.

resultsA total of 243 UPHs occurred (2.5 cases/100 person-years). Fontan-related UPHs accounted for 154 cases (63%), most commonly due to heart failure (19%), protein-losing enteropathy (16%), hemorrhage (14%), arrhythmia (9%), thromboembolism (3%), and plastic bronchitis (2%). Fontan-unrelated UPHs (89 cases; 37%) were mainly due to infections (19%). Adult patients were more frequently hospitalized for hemorrhage and thromboembolism (

conclusionsWe clarified real-world practices related to UPHs in Fontan patients. Specific in-hospital treatment strategies were associated with the risk of readmission. Further studies are warranted to determine the causal relationships between treatment approaches and outcomes for standardized management strategies.

Indexed as

Fontan ProcedureHeart Defects, CongenitalHospitalizationPostoperative ComplicationsAdolescentAdultChildChild, PreschoolFemaleHeart FailureHumansLength of StayMaleProspective StudiesProtein-Losing EnteropathiesRisk FactorsFontanheart failurehospitalizationmanagementprotein‐losing enteropathy

Identifiers

PMID41368820
PMCPMC12826895

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.