Evidence map›Paper›PMID 41368591›Full record

SynthesisDepression and anxiety2025

Bidirectional Relationship Between Myopia and Mental Disorders.

Dan-Lin Li, Su-Tong Yu, Li-Jun Zhang, Xiao-Feng Zhang, Chen-Wei Pan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Depression and anxiety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dan-Lin LiSchool of Public Health, Suzhou Medical College of Soochow University, Suzhou, China.ORCID 0000-0003-0800-4308
Su-Tong YuSuzhou Medical College of Soochow University, Suzhou, China.ORCID 0009-0001-6359-1755
Li-Jun ZhangDepartment of Ophthalmology, Dalian Third People's Hospital Affiliated to Dalian University of Technology, Dalian, China.ORCID 0000-0003-4254-739X
Xiao-Feng ZhangDepartment of Ophthalmology, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0009-0007-3904-3832
Chen-Wei PanSchool of Public Health, Suzhou Medical College of Soochow University, Suzhou, China.ORCID 0000-0003-3362-4613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myopia and mental disorders share common environmental and behavioral risk factors. Previous studies have been inconsistent regarding the association between them, this systematic review and meta-analysis aims to explore the association between myopia and mental disorders. Methods: Databases, including PubMed, Web of Science, Wiley online library, and Cochrane Library were searched for eligible publications from January 2000 to July 2024. Studies assessing the relationship between myopia and any one of the mental disorders were identified. Pooled odds ratios (ORs) and their corresponding 95% confidence intervals (95% CIs) were estimated using random-effects models. Results: We identified 15 articles (two cohort studies and 13 cross-sectional studies) examining the impact of myopia on mental disorders, involving 2,841,653 participants from seven countries. Pooled results indicated that myopia was significantly associated with an increased risk of mental disorders (OR = 1.41, 95% CI: 1.23, 1.59). Besides, a significant relationship was observed between the mental disorders and myopia (OR = 1.15, 95% CI: 1.01, 1.29) based on eight articles, including 1,942,855 participants from five countries. Subgroup analyses showed that the association of myopia with both anxiety and depression was significant, with ORs of 1.49 and 1.33, respectively. Conclusions: Myopia and mental disorders may influence each other, with each condition potentially exacerbating the risk of the other. These findings help to explore the possible interplay between mental disorders and myopia.

Indexed as

Anxiety DisordersMental DisordersMyopiaComorbidityHumansbidirectional relationshipmental disordersmyopia

Identifiers

PMID41368591
PMCPMC12685417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.