Evidence map›Paper›PMID 41368569›Full record

SynthesisFrontiers in pharmacology2025

The impact of climate change on medicinal plants and natural products: A scoping review.

Marce Inggritha Takubessi, Banaz Jalil, Michael Heinrich

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Predicting the Potential Distribution ofPlants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marce Inggritha TakubessiResearch Group "Pharmacognosy and Phytotherapy", UCL School of Pharmacy, London, United Kingdom.
Banaz JalilResearch Group "Pharmacognosy and Phytotherapy", UCL School of Pharmacy, London, United Kingdom.
Michael HeinrichResearch Group "Pharmacognosy and Phytotherapy", UCL School of Pharmacy, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Medicinal plants and natural products are essential for healthcare systems globally, and, at the same time, they are a part of ecosystems and have major socioeconomic importance in many regions of the world. However, climate change has threatened their supply and sustainability. In this review, we map the current state of research on how climate change affects medicinal plants, focusing on ecological shifts, traditional uses, changes in bioactive metabolites, and adaptation strategies. Methods: This scoping review, which was conducted following the PRISMA-ScR guidelines, involved comprehensive searches in PubMed, Scopus, and Web of Science of studies published between 2004 and 2024. Data were extracted to summarize study characteristics, climate change factors, species distribution, bioactive metabolites and marker compounds variations, and healthcare implications. Results: A total of 219 studies were included, showing a significant increase in publication after 2021. Most studies were conducted in Asia, especially in China and India, whereas Europe, Africa, and South America remain underrepresented. The review covers 367 medicinal plant species, including high-altitude, climate-sensitive species such as Conclusion: Climate change is reshaping the ecology and pharmacological value of medicinal plants. Although adaptation strategies exist, their implementation remains limited. An interdisciplinary, coordinated response is urgently needed to ensure sustainable production and use. This will also require a paradigm shift in all aspects of ethnopharmacological research and development.

Indexed as

bioactive natural productsclimate changeGIS-based ecological assessmentsMaxEntmedicinal plantsspecies distribution modelingtraditional medicine

Identifiers

PMID41368569
PMCPMC12682780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.