ReviewAnnals of nuclear cardiology2025
The Fading Art of Microsphere-Derived Measurement of Absolute Myocardial Blood Flow.
Review in Annals of nuclear cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The measurement of absolute myocardial blood flow (MBF) has played a pivotal role in the development of nuclear cardiology and other perfusion imaging techniques. However, the capacity to perform such experiments may be diminished. This review examines the basic physiology of microsphere measurement of absolute MBF which was developed over 50 years ago, with multiple refinements over time. The use of different types of microspheres is presented in depth. The set-up and performance of a large animal model is detailed with tips and pitfalls explained. It is the purpose of this review to stimulate the next generation of investigators into considering this skill as part of their research tool box.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.