ReviewInfection and drug resistance2025
Application and Limitations of 16S rRNA Gene Sequencing for Identifying WHO Priority Pathogenic Gram-Negative Bacilli.
Review in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Article
- Stenotrophomonas mexicanensis subsp. fluminensis subsp. nov., a new subspecies isolated from a clinical sample at a hospital in Rio de Janeiro, Brazil, during COVID-19 pandemic.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Biotechnological potential of marine invertebrate-associated bacteria with antibacterial activity against aquaculture and human pathogens.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- The Gut-Brain-Immune Axis: Multi-Omics Insights into Neurodegenerative and Metabolic Diseases.Cells · 2026Review
- From genome to field, biocontrol efficacy of Bacillus subtilis strain M10 against Rhizoctonia solani in common bean.Scientific reports · 2026Article
- Genomic, metabolomic, and functional properties of probiotic lactic acid bacteria isolated from Indonesian stingless bee honey.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- The Vaginal Microbiome and Host Health: Implications for Cervical Cancer Progression.International journal of molecular sciences · 2026Review
- Biliary tract microbes and common bile duct stones: current status and prospects.Frontiers in microbiology · 2026Review
- 16S rRNA-based genetic diversity and symbiotic efficiency of indigenous cowpea-nodulating rhizobia from semiarid Eastern Kenya.Frontiers in microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance (AMR) poses one of the greatest global health challenges, particularly in healthcare-associated infections caused by multidrug-resistant Gram-negative bacilli. Rapid and reliable identification of these pathogens is critical to guide therapy, improve patient outcomes, and support infection control measures. This review explores the application of 16S ribosomal RNA (rRNA) gene sequencing for the identification of pathogenic Gram-negative bacilli included in the World Health Organization (WHO) antimicrobial resistance priority list. The 16S rRNA gene, with its conserved and hypervariable regions, provides a robust molecular marker widely used in bacterial taxonomy and clinical diagnostics. The analysis covers conventional Sanger sequencing, next-generation sequencing (NGS), and third-generation approaches, outlining their advantages, limitations, and clinical applicability. Results indicate that while 16S rRNA sequencing is a valuable tool for genus-level identification, comparative analysis reveals its resolution is often insufficient for distinguishing closely related species such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.