Evidence map›Paper›PMID 41368448›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2025

Maternal and Fetal Outcomes in Pregnant Women Admitted to the Intensive Care Unit with A/H1N1pdm or SARS-CoV-2 Infection: A Retrospective Study.

Vineeth V Thomas, Guruckeeran Nakkeeran, Kirthana R Jacob, Binila Chacko, Mahesh Moorthy, Mahasampath Gowri, Richa Tirkey, Krupa George, Sudha Jasmine, Samuel Hansdak and 5 more

Abstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Vineeth V ThomasDepartment of Critical Care, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-6254-3030
Guruckeeran NakkeeranDepartment of Critical Care, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0002-4470-6219
Kirthana R JacobDepartment of Obstetrics and Gynaecology, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0007-6479-462X
Binila ChackoDepartment of Critical Care, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-1609-2208
Mahesh MoorthyDepartment of Virology, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-6040-040X
Mahasampath GowriDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-0251-0763
Richa TirkeyDepartment of Obstetrics and Gynaecology, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-4956-9631
Krupa GeorgeDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0002-5273-5327
Sudha JasmineDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0003-4852-9301
Samuel HansdakDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-3389-1220
Jonathan JayakaranDepartment of Internal Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0001-7045-2457
Sujith ChandyDepartment of Respiratory Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0003-4118-3846
Benjamin WilliamsDepartment of Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-9183-1250
Divya DeodharDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0009-0001-8190-8218
John V PeterDepartment of Critical Care, Christian Medical College, Vellore, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-3423-1830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: It is unclear if maternal and fetal outcomes of pregnant women admitted to the intensive care unit (ICU) with A/H1N1pdm and SARS-CoV-2 infection are different. Patients and methods: This retrospective study (2007-2022) included pregnant women admitted to the ICU with real-time reverse transcription polymerase chain reaction-confirmed A/H1N1pdm or SARS-CoV-2 pneumonia; non-viral pneumonia and incomplete records were excluded. The primary outcome was maternal mortality. Secondary outcomes included need for organ support, duration of ventilation, hospital stay, and fetal outcome. Predictors of maternal mortality were explored using multivariate logistic regression. Results: Fifty-six women (A/H1N1pdm = 42, SARS-CoV-2 = 14) were admitted to the ICU at a median (interquartile) gestational age of 32.3 (27.3-36) weeks. Gestational diabetes ( Conclusion: Respiratory failure due to A/H1N1pdm and SARS-CoV-2 infections in pregnancy is associated with high maternal mortality and fetal loss. Delayed presentation is independently associated with maternal death. How to cite this article: Thomas VV, Nakkeeran G, Jacob KR, Chacko B, Moorthy M, Gowri M,

Indexed as

Intensive careMaternal mortalityNeonatal outcomePregnancyRespiratory failureViral infection

Identifiers

PMID41368448
PMCPMC12683557

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.