Evidence map›Paper›PMID 41368412›Full record

ArticleJTCVS techniques2025

Mid-term outcomes of a modified prosthetic aortic valve implantation technique for prosthetic valve endocarditis complicated by aortic annular abscess.

Giuseppe Nasso, Walter Vignaroli, Raffaele Bonifazi, Flavio Fiore, Giacomo Schinco, Felice Agrò, Ernesto Greco, Antongiulio Valenzano, Giacomo Errico, Dritan Hila and 3 more

Abstract read
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Article in JTCVS techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Giuseppe NassoDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Walter VignaroliDepartment of Cardiac Surgery, San Carlo di Nancy Hospital GVM Care & Research, Rome, Italy.
Raffaele BonifaziDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Flavio FioreDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Giacomo SchincoDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Felice AgròAnesthesia and Intensive Care Research Unit, Campus Bio-Medico University, Rome, Italy.
Ernesto GrecoDepartment of Health and Life Sciences, European University of Rome, Rome, Italy.
Antongiulio ValenzanoDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Giacomo ErricoDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Dritan HilaDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Tommaso LoizzoDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.
Giuseppe SantarpinoDepartment of Cardiac Surgery, Città di Lecce Hospital, GVM Care & Research, Lecce, Italy.
Giuseppe SpezialeDepartment of Cardiac Surgery, Anthea Hospital and Santa Maria Hospital GVM Care & Research, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prosthetic valve endocarditis (PVE) complicated by complex paraannular aortic abscess remains a surgical challenge. We aimed to evaluate the mid-term outcomes of a standardized, patch-free, supra-annular aortic valve replacement strategy that avoids complete root replacement in these high-risk patients. Methods: This retrospective, single-center study included 70 consecutive patients treated between 2015 and 2023 for complex aortic PVE using a consistent surgical protocol: radical debridement, supra-annular prosthetic valve implantation, inside the Valsalva sinuses, and external felt reinforcement-without annular or root patching. Follow-up included annual clinical and echocardiographic assessment (mean duration, 5.2 ± 1.3 years). The primary endpoint was freedom from the composite of reinfection or aortic reoperation. Secondary endpoints included survival, valve performance, and predictors of late adverse events. Results: Hospital mortality was 5.7% (n = 4 of 70). At 5 years, overall survival was 86.0% (95% confidence interval [CI], 78.0%-93.9%), and freedom from reinfection or aortic reoperation was 89.2% (95% CI, 82.1%-96.2%). Outcomes were comparable between the original (n = 47) and expanded (n = 23) cohorts (log-rank Conclusions: Patch-free supra-annular valve replacement offers durable infection control and excellent hemodynamic outcomes, avoiding the need for complete root replacement in complex aortic PVE.

Indexed as

aortic valve endocarditisaortic valve replacementendocarditissupra-annular valve replacement

Identifiers

PMID41368412
PMCPMC12683027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.