Evidence map›Paper›PMID 41368410›Full record

ArticleJTCVS techniques2025

Aortoesophageal fistula: Long-term survival with aggressive multidisciplinary management.

Rolando Calderon-Rojas, Brett Curran, Belisario A Ortiz, Harrison Herrera, Dennis A Wigle, Stephen D Cassivi, Janani Reisenauer, K Robert Shen, Randall DeMartino, Todd Rasmussen and 4 more

Abstract read
In one paragraph

Article in JTCVS techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rolando Calderon-RojasDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Brett CurranDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Belisario A OrtizDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Harrison HerreraDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Dennis A WigleDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Stephen D CassiviDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Janani ReisenauerDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
K Robert ShenDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.
Randall DeMartinoDivision of Vascular Surgery, Mayo Clinic, Rochester, Minn.
Todd RasmussenDivision of Vascular Surgery, Mayo Clinic, Rochester, Minn.
Alberto PochettinoDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Kevin GreasonDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Malakh ShresthaDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Luis F TapiasDivision of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Aortoesophageal fistula (AoEF) is a rare but complex problem that carries high mortality. This study describes our institutional experience with the management of AoEF. Methods: There were 17 patients with AoEF who were managed in our center (2005-2023). Medical records were reviewed for baseline characteristics, history of esophageal or aortic disease, diagnostic evaluation, surgical treatment, and follow-up. Overall survival (OS) was analyzed using the Kaplan-Meier method and log rank tests. Results: Most patients had previous aortic operations (12/17, 71%)-7 thoracic endovascular aortic repair (TEVAR), 3 open/TEVAR, and 2 open repairs. The etiology of AoEF was aortic disease in 13 (76%) and anastomotic leak after esophagectomy in 4 (24%). Upon presentation, 2 (12%) patients were not offered intervention, whereas 6 (35%) had emergency TEVAR to control bleeding. Twelve (67%) patients were treated with curative intent, 1 patient did not survive an initial aortic operation. Of the remaining 11 patients, esophageal operations happened before aortic repair in 7 (64%), concurrently in 3 (27%), and after in 1 (9%). This included diversion esophagectomy in 7 (64%) and primary repair in 3 (27%). Definitive aortic surgery included aorta replacement with rifampin-soaked grafts in 8 (67%) and homografts in 4 (33%). In-hospital mortality occurred in 1 of 12 (8%) cases. One- and 2-year OS was 83% and 74%. OS was lower in patients not receiving curative-intent treatment ( Conclusions: Management of AoEF is complex. However, aggressive multidisciplinary intervention with definitive esophageal and aortic repairs can result in good long-term survival in selected patients.

Indexed as

aortoesophageal fistulaesophageal fistula repairthoracic endovascular aortic repair

Identifiers

PMID41368410
PMCPMC12683045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.