ArticleAnnals of surgical treatment and research2025
Surgical treatment of papillary thyroid cancer diagnosed during pregnancy: a retrospective, single-center, case-control study.
Article in Annals of surgical treatment and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Papillary thyroid cancer (PTC), a common malignancy among women of reproductive age, is increasingly common during pregnancy because of routine prenatal imaging. However, the optimal timing for surgical treatment remains controversial. This study aimed to assess the safety and practicality of performing thyroid surgery during pregnancy through a comparative analysis of perioperative and pathological outcomes between pregnant and nonpregnant women. Methods: We conducted a retrospective case-control study of 100 female patients aged 20-39 years who underwent thyroid surgery for PTC between January 2019 and December 2024. Patients were grouped into pregnant (n = 14) and nonpregnant (n = 86) cohorts. Clinical, surgical, and pathological data were compared. Results: Most pregnant patients underwent surgery during the second trimester. The operative duration was significantly shorter in the pregnant group than in the nonpregnant group (71.4 ± 26.35 minutes Conclusion: Thyroid surgery during pregnancy, particularly in the second trimester, appears feasible in selected patients. Given the small sample and retrospective nature of this study, larger prospective studies are needed to validate these findings.
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