ArticleFrontiers in medicine2025
Impact of stair climbing volume on patellofemoral cartilage: a dose-response analysis from the osteoarthritis initiative reveals elevated risk at middle levels.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Objective: To evaluate the impact of stair climbing volume on cartilage degeneration in the patellofemoral joint, with a particular focus on the medial/lateral patellar and trochlear regions. Methods: Utilizing data from the osteoarthritis initiative (OAI) cohort, we analyzed 581 participants with baseline and 24-month follow-up MRI assessments. Cartilage damage was evaluated using the MRI Osteoarthritis Knee Score (MOAKS), with subregional stratification (medial/lateral patella, medial/lateral trochlea). Stair-climbing volume was categorized as low (0-4 flights/week), middle (5-6 flights/week), or high (> 6 flights/week). Logistic regression models adjusted for BMI, age, and sex assessed the dose-response relationship between stair climbing and cartilage deterioration across patellofemoral subregions. Results: A total of 581 participants were included (59.4% female, age 61.6 ± 8.9 years, BMI = 30.7 ± 4.7 kg/m Conclusion: Middle-volume stair climbing was associated with greater progression of patellofemoral joint cartilage deterioration, particularly in the trochlear region, suggesting that mechanical loading patterns during stair climbing may influence subregional cartilage vulnerability.
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