Evidence map›Paper›PMID 41368084›Full record

ArticleBiomedical optics express2025

Cleared tissue dual-view oblique plane microscopy.

L Dvinskikh, H Sparks, L Rowe-Brown, W Hong, D Ennis, R Sarnataro, D Carreno, F S Tissot, C Lo Celso, D T Riglar and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

L DvinskikhDepartment of Physics, Imperial College London, UK.ORCID https://orcid.org/0000-0002-9020-8862
H SparksDepartment of Physics, Imperial College London, UK.ORCID https://orcid.org/0000-0001-9900-6610
L Rowe-BrownDepartment of Physics, Imperial College London, UK.
W HongDepartment of Physics, Imperial College London, UK.ORCID https://orcid.org/0000-0002-8781-8627
D EnnisDepartment of Surgery and Cancer, Imperial College London, UK.
R SarnataroCentre for Neural Circuits and Behaviour, University of Oxford, UK.ORCID https://orcid.org/0000-0002-2977-542X
D CarrenoThe Francis Crick Institute, UK.
F S TissotThe Francis Crick Institute, UK.
C Lo CelsoThe Francis Crick Institute, UK.
D T RiglarThe Francis Crick Institute, UK.
P CunneaDepartment of Surgery and Cancer, Imperial College London, UK.
I A McNeishDepartment of Surgery and Cancer, Imperial College London, UK.
C DunsbyDepartment of Physics, Imperial College London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a dual-view oblique plane microscope (dOPM) for imaging thick optically cleared tissue samples using a silicone immersion primary objective. The custom-designed remote refocusing relay utilizes stock optics to achieve remote refocusing in refractive index-matched samples. The spatial resolution of the system was characterized using a series of fluorescent bead phantoms with refractive indices ranging from 1.4-1.5, with the point spread function full width at half maximum measuring ∼0.5 µm laterally and ∼1 µm axially for a refractive index-matched bead sample, with minimal degradation over a > 250 µm axial range. We characterize how the remote refocusing performance at sample refractive indices up to

Identifiers

PMID41368084
PMCPMC12684026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.