Evidence map›Paper›PMID 41368066›Full record

ArticleClinical case reports2025

Paliperidone-Induced Catatonia: Case Series and Review of Literature.

Sikandar Saeed, Sakshi Prasad, Arham Javaid, Elzar Matmusaeva, Marcos Rocha, Resha Karani, Samkit Jain, Khai Tran, Sasidhar Gunturu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sikandar SaeedBronxCare Health System New York New York USA.
Sakshi PrasadBronxCare Health System New York New York USA.ORCID https://orcid.org/0000-0002-1014-9031
Arham JavaidBronxCare Health System New York New York USA.
Elzar MatmusaevaBronxCare Health System New York New York USA.
Marcos RochaSchool of Medicine American University of the Caribbean Cupecoy Sint Maarten.
Resha KaraniAmerican University of Antigua College of Medicine Coolidge Antigua and Barbuda.
Samkit JainVinnytsya National Medical University Vinnitsiya Ukraine.ORCID https://orcid.org/0009-0008-7975-1195
Khai TranBronxCare Health System New York New York USA.
Sasidhar GunturuBronxCare Health System New York New York USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paliperidone, a second-generation antipsychotic commonly used to treat schizophrenia and schizoaffective disorder, has been rarely associated with inducing catatonia, a severe neuropsychiatric syndrome characterized by motor disturbances and altered mental status. We present two cases demonstrating variable onset of paliperidone-induced catatonia: a 20-year-old male with acute symptoms following intramuscular loading doses and a 24-year-old female with a delayed presentation. Both cases highlight the clinical challenge of timely recognition, which is critical to prevent serious complications such as dehydration and respiratory failure. Assessment using the Bush-Francis Catatonia Rating Scale (BFCRS) guided treatment with benzodiazepines and antipsychotic adjustments, resulting in significant symptom improvement. This case series underscores the need for heightened awareness of this rare adverse effect to facilitate early diagnosis and optimize outcomes in patients receiving paliperidone.

Indexed as

case reportcatatonialong acting injectablepaliperidonepsychopharmacology

Identifiers

PMID41368066
PMCPMC12682600

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.