Evidence map›Paper›PMID 41368031›Full record

ArticleFrontiers in veterinary science2025

Revealing the genetic basis of coat color in Tibetan sheep through selective sweep and transcriptomic analyses.

Xue Li, Buying Han, Dehong Tian, Dehui Liu, Wulong Ma, Guangcai Bao, Lei Wang, Quanbang Pei, Zian Zhang, Kai Zhao

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In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xue LiKey Laboratory of Adaptation and Evolution of Plateau Biota, Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.
Buying HanKey Laboratory of Adaptation and Evolution of Plateau Biota, Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.
Dehong TianKey Laboratory of Adaptation and Evolution of Plateau Biota, Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.
Dehui LiuKey Laboratory of Adaptation and Evolution of Plateau Biota, Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.
Wulong MaMenyuan County Agriculture, Animal Husbandry and Water Conservancy Comprehensive Service Center, Menyuan, Qinghai, China.
Guangcai BaoQinghai Provincial Agricultural Project Guidance Service Center, Xining, Qinghai, China.
Lei WangQinghai Sheep Breeding and Promotion Service Center, Gangcha, Qinghai, China.
Quanbang PeiQinghai Sheep Breeding and Promotion Service Center, Gangcha, Qinghai, China.
Zian ZhangQinghai Sheep Breeding and Promotion Service Center, Gangcha, Qinghai, China.
Kai ZhaoKey Laboratory of Adaptation and Evolution of Plateau Biota, Qinghai Provincial Key Laboratory of Animal Ecological Genomics, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, Qinghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Coat color is an important economic trait in animal husbandry and plays a crucial role in the adaptability of animal. As a key economic trait in high-altitude areas, the genetic mechanisms regulating coat color in Tibetan sheep are not fully understood. Methods: In order to explore the genetic basis of coat color in Tibetan sheep, this study focused on white-coated Plateau Tibetan sheep (PT) and black-coated Guinan black fur sheep (GB). Using whole genome sequencing (10× coverage), transcriptomic analysis, Sanger sequencing, and protein structure prediction to identify candidate genes and molecular markers associated with coat color. Results: In this study, a total of 9.28 million SNPs were annotated from whole-genome sequencing. Compared with the white-coated PT sheep, the skin transcriptome of black-coated GB sheep exhibited 659 up-regulated and 426 down-regulated genes. Conclusion: Two molecular markers (rs3508196008 and rs409651063) in the

Indexed as

coat colormolecular markersRNA-seqTibetan sheepwhole genome sequencing

Identifiers

PMID41368031
PMCPMC12682660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.